SCHEMBL7200522

SCHEMBL7200522

N=C(c1ccccc1)c1cccc2c1O2

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.40
AHR P35869 3/20 0.38
F2 P00734 1/20 0.35
F10 P00742 1/20 0.35
F12 P00748 1/20 0.35
F7 P08709 1/20 0.35
F3 P13726 1/20 0.35
PKM P14618 1/20 0.35
BLM P54132 1/20 0.34
TRPA1 O75762 4/20 0.33
PRSS1 P07477 3/20 0.33
PRSS2 P07478 3/20 0.33
PRSS3 P35030 3/20 0.33
P2RX4 Q99571 1/20 0.33
C1S P09871 1/20 0.33
RECQL P46063 1/20 0.33
KMT2A Q03164 1/20 0.33
ALOX5 P09917 1/20 0.33
CYP2C9 P11712 2/20 0.33
AKR1C3 P42330 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27909830 0.77 AKR1C3 (0.53) PKMKMT2ACYP2C9AKR1C3NR4A1
SCHEMBL28794373 0.76 CYP1A2 (0.52) CYP1A2F2F10F12F7
SCHEMBL6530620 0.71 ALDH1A1 (0.50) TRPA1ALOX5CYP2C9AKR1C3NR4A1
SCHEMBL6445212 0.71 CYP2C9 (0.53) AHRTRPA1ALOX5CYP2C9AKR1C3
SCHEMBL23709160 0.69 NR4A1 (0.57) CYP1A2KMT2ACYP2C9CYP2D6CYP2C19
Water SCHEMBL27710341 0.69 ALDH1A1 (0.48) TRPA1ALOX5CYP2C9AKR1C3NR4A1
SCHEMBL27710338 0.69 ALDH1A1 (0.48) TRPA1ALOX5CYP2C9AKR1C3NR4A1
SCHEMBL31391623 0.69 TRPA1 (0.41) AHRTRPA1P2RX4KMT2AALOX5
SCHEMBL50746 0.69 HPGD (0.50) CYP1A2F2F10F12F7
SCHEMBL27411702 0.68 F2 (0.58) CYP1A2F2F10F12F7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1304924-A2 COMPOSITIONS FOR REPELLING CRAWLING INSECTS Bayer Aktiengesellschaft (DE) 2003-05-02 EP disclosed
WO-2002005646-A2 COMPOSITIONS FOR REPELLING CRAWLING INSECTS S.C. JOHNSON & SON, INC. (US) (US) 2002-01-24 WO disclosed