Sugi Predict

Sugi Predict / Compounds / SCHEMBL50746

SCHEMBL50746

SCHEMBL50746

N=C(c1ccccc1)c1ccccc1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HPGD P15428 7/20 0.50
▸ KDM4E B2RXH2 7/20 0.50
▸ SMN1; SMN2 Q16637 4/20 0.50
▸ ALDH1A1 P00352 4/20 0.50
▸ CA12 O43570 2/20 0.50
▸ CA2 P00918 2/20 0.50
▸ CA4 P22748 2/20 0.50
▸ CA14 Q9ULX7 2/20 0.50
▸ CA1 P00915 1/20 0.50
▸ HMGB1 P09429 1/20 0.50
▸ CA6 P23280 1/20 0.50
▸ CA7 P43166 1/20 0.50
▸ CA9 Q16790 1/20 0.50
▸ NAPRT Q6XQN6 1/20 0.50
▸ MAPT P10636 3/20 0.47
▸ CYP3A4 P08684 2/20 0.47
▸ CYP1A2 P05177 1/20 0.46
▸ HSD17B10 Q99714 4/20 0.43
▸ TSHR P16473 2/20 0.43
▸ GSTA1 P08263 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29132386 0.86 LIG1 (0.59) HPGDKDM4ESMN1; SMN2ALDH1A1CA12
SCHEMBL7184700 0.86 HPGD (0.57) HPGDKDM4ESMN1; SMN2ALDH1A1CA12
SCHEMBL28794373 0.85 CYP1A2 (0.52) HPGDKDM4ESMN1; SMN2ALDH1A1CA12
SCHEMBL9130593 0.85 HPGD (0.52) HPGDKDM4ESMN1; SMN2ALDH1A1CA12
SCHEMBL758247 0.83 HPGD (0.45) HPGDKDM4ESMN1; SMN2ALDH1A1CA12
SCHEMBL8346552 0.82 HPGD (0.50) HPGDKDM4ESMN1; SMN2ALDH1A1CA12
SCHEMBL25306705 0.78 ALDH1A1 (0.49) HPGDKDM4ESMN1; SMN2ALDH1A1F7
SCHEMBL4715956 0.76 HPGD (0.50) HPGDKDM4ESMN1; SMN2ALDH1A1CA12
SCHEMBL16954 0.76 F2 (0.58) HPGDKDM4ESMN1; SMN2ALDH1A1CA12
SCHEMBL7535150 0.76 CYP1A2 (0.58) HPGDKDM4ESMN1; SMN2ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1363923-B1 RHODIUM AND IRIDIUM COMPLEXES MERCK PATENT GMBH (DE) 2009-04-01 — — EP claimed
US-7125998-B2 Rhodium and iridium complexes MERCK PATENT GMBH (DE) 2006-10-24 — — US claimed
EP-1562964-B1 PALLADIUM AND PLATINUM COMPLEXES MERCK PATENT GMBH (DE) 2006-07-19 — — EP claimed
US-20040138455-A1 Rhodium and iridium complexes MERCK PATENT GMBH (DE) 2004-07-15 — — US claimed
US-11917901-B2 Metal complexes UDC IRELAND LIMITED (IE) 2024-02-27 — — US disclosed
US-20230403927-A1 AROMATIC COMPOUNDS UDC IRELAND LTD (IE) 2023-12-14 — — US disclosed
US-11800787-B2 Metal complexes UDC IRELAND LIMITED (IE) 2023-10-24 — — US disclosed
US-20230056324-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2023-02-23 — — US disclosed
US-11390774-B2 Curable coating compositions containing poly activated methylene resins and polyisocyanates PPG INDUSTRIES OHIO, INC. (US) 2022-07-19 — — US disclosed
US-20220209141-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2022-06-30 — — US disclosed
EP-3956338-A1 METAL COMPLEXES Merck Patent GmbH (DE) 2022-02-23 — — EP disclosed
US-11192909-B2 Method for the separation of enantiomeric mixtures from metal complexes MERCK PATENT GMBH (DE) 2021-12-07 — — US disclosed
US-20060071206-A1 Palladium and platinum complexes UDC IRELAND LIMITED (IE) 2006-04-06 — — US disclosed
US-20050253135-A1 Rhodium and iridium complexes MERCK PATENT GMBH (DE) 2005-11-17 — — US disclosed
US-20040138455-A1 Rhodium and iridium complexes MERCK PATENT GMBH (DE) 2004-07-15 — — US disclosed
EP-1304924-A2 COMPOSITIONS FOR REPELLING CRAWLING INSECTS Bayer Aktiengesellschaft (DE) 2003-05-02 — — EP disclosed
WO-2003018662-A1 CATALYSTS AND CURABLE COMPOSITIONS JOHNSON MATTHEY PLC (GB) 2003-03-06 — — WO disclosed
US-20020094993-A1 Compositions for repelling crawling insects S.C. JOHNSON & SON, INC. 2002-07-18 — — US disclosed
WO-2002005646-A2 COMPOSITIONS FOR REPELLING CRAWLING INSECTS S.C. JOHNSON & SON, INC. (US) (US) 2002-01-24 — — WO disclosed
US-5208260-A Vinyl Glycine derivatives for memory and learning enhancement or treatment of a cognitive disorder G. D. SEARLE & CO. (US) 1993-05-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040138455-A1 Rhodium and iridium complexes RPIA, MPI, INPP5B HPGD 1683/4885KDM4E 2466/4885SMN1; SMN2 4239/4885
US-20050253135-A1 Rhodium and iridium complexes RPIA, SIRT5, RAB35 HPGD 1910/4885KDM4E 4203/4885SMN1; SMN2 4137/4885
US-11192909-B2 Method for the separation of enantiomeric mixtures from metal complexes AP2M1, AP1M1, AP3M1 HPGD 3656/4885KDM4E 3694/4885SMN1; SMN2 4504/4885
US-20230056324-A1 METAL COMPLEXES MCU, IMMT, SOD1 HPGD 3581/4885KDM4E 4474/4885SMN1; SMN2 4259/4885
US-20230403927-A1 AROMATIC COMPOUNDS TYR, CTCF, MITF HPGD 3952/4885KDM4E 1344/4885SMN1; SMN2 4401/4885
US-20220209141-A1 METAL COMPLEXES AP1M1, SOD1, AP3M1 HPGD 3841/4885KDM4E 3628/4885SMN1; SMN2 4073/4885
US-11800787-B2 Metal complexes AP1M1, SOD1, AP3M1 HPGD 3884/4885KDM4E 3544/4885SMN1; SMN2 3925/4885
US-20020094993-A1 Compositions for repelling crawling insects ACHE, DDT, GAP43 HPGD 3530/4885KDM4E 3406/4885SMN1; SMN2 2971/4885
US-20060071206-A1 Palladium and platinum complexes PMS2, PDCD1, PDCD1LG2 HPGD 2215/4885KDM4E 3929/4885SMN1; SMN2 2476/4885
US-11917901-B2 Metal complexes MCOLN2, MCOLN1, AP1M1 HPGD 3283/4885KDM4E 4260/4885SMN1; SMN2 1541/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.