Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 8/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 10/20 | 0.36 |
| ▸ | AR | P10275 | 7/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 3/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.30 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7199636 | 0.86 | PGR (0.34) | PGRNR3C1ARCYP3A4 | |
| SCHEMBL8536675 | 0.86 | PGR (0.50) | PGRNR3C1ARCYP3A4ESR1 | |
| SCHEMBL7200581 | 0.86 | PGR (0.50) | PGRNR3C1ARCYP3A4ESR1 | |
| SCHEMBL9019818 | 0.86 | PGR (0.50) | PGRNR3C1ARCYP3A4ESR1 | |
| SCHEMBL8768221 | 0.86 | PGR (0.50) | PGRNR3C1ARCYP3A4ESR1 | |
| SCHEMBL7197531 | 0.84 | NR3C1 (0.34) | PGRNR3C1ARCYP3A4 | |
| SCHEMBL8653821 | 0.82 | PGR (0.47) | PGRNR3C1ARCYP3A4ESR1 | |
| SCHEMBL7198823 | 0.82 | NR3C1 (0.34) | PGRNR3C1ARCYP3A4 | |
| SCHEMBL8767962 | 0.77 | PGR (0.32) | PGRNR3C1AR | |
| SCHEMBL8767741 | 0.75 | NR3C1 (0.30) | PGRNR3C1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596713-B1 | Antigestagenic, antiglucocorticoidal, antimineralcorticoidal or antiandrogenic effect | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-07-22 | — | — | US | disclosed |