SCHEMBL7200642

SCHEMBL7200642

CCCCCCCCCCCCCCCCCCNC(=O)C(=O)NCCCc1ccc(O)c(O)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 4/20 0.68
GPR119 Q8TDV5 1/20 0.66
MAPT P10636 4/20 0.65
HSD17B10 Q99714 3/20 0.65
MEN1 O00255 2/20 0.65
KMT2A Q03164 2/20 0.65
HPGD P15428 3/20 0.57
KDM4E B2RXH2 2/20 0.57
LMNA P02545 2/20 0.57
BLM P54132 2/20 0.57
HIF1A Q16665 2/20 0.57
NPC1 O15118 1/20 0.57
GMNN O75496 1/20 0.57
USP2 O75604 1/20 0.57
TP53 P04637 1/20 0.57
CYP1A2 P05177 1/20 0.57
POLB P06746 1/20 0.57
CYP3A4 P08684 1/20 0.57
CYP2C9 P11712 1/20 0.57
IDE P14735 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8390662 0.86 TRPV1 (0.87) TRPV1GPR119MAPTHSD17B10MEN1
SCHEMBL7108607 0.86 MAPT (0.73) TRPV1GPR119MAPTHSD17B10MEN1
SCHEMBL1278764 0.86 MAPT (0.73) TRPV1GPR119MAPTHSD17B10MEN1
Hydrocaffeoylhexylamide SCHEMBL9346647 0.84 TRPV1 (0.80) TRPV1GPR119MAPTHSD17B10MEN1
SCHEMBL9350021 0.84 TRPV1 (0.80) TRPV1GPR119MAPTHSD17B10MEN1
SCHEMBL9345367 0.84 TRPV1 (0.80) TRPV1GPR119MAPTHSD17B10MEN1
SCHEMBL7269071 0.84 ESR1 (0.64) TRPV1HSD17B10HPGDKDM4ELMNA
SCHEMBL7269077 0.84 ESR1 (0.64) TRPV1HSD17B10HPGDKDM4ELMNA
SCHEMBL7197022 0.84 ESR1 (0.64) TRPV1HSD17B10HPGDKDM4ELMNA
SCHEMBL7264214 0.84 ESR1 (0.64) TRPV1HSD17B10HPGDKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6596669-B1 Comprising a support and two reversible heat-sensitive recording layers having different colors formed on the same side of the support, comprising colorless electron-donative dye precursor and an electron-accepting compound MITSUBISHI PAPER MILLS LIMITED (JP) 2003-07-22 US disclosed
US-6004899-A SURFACE TREATED WITH SILANE, TITANATE, AND/OR ALUMINUM COUPLING AGENT; PIGMENT; ERASIBILITY MITSUBISHI PAPER MILLS LIMITED (JP) 1999-12-21 US disclosed
EP-0648612-B1 Reversible heat-sensitive recording material MITSUBISHI PAPER MILLS LTD (JP) 1998-06-10 EP disclosed
US-5498772-A SUBSTRATE WITH HEAT SENSITIVE LAYER AND OPTICAL RECORDING LAYER MITSUBISHI PAPER MILLS LIMITED (JP) 1996-03-12 US disclosed
EP-0648612-A1 Reversible heat-sensitive recording material MITSUBISHI PAPER MILLS, LTD. (JP) 1995-04-19 EP disclosed