Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 6/20 | 0.32 |
| ▸ | MAOA | P21397 | 3/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6152348 | 0.76 | OPRM1 (0.38) | MAOBMAOA | |
| SCHEMBL10669578 | 0.71 | MAPT (0.39) | GAAHTT | |
| SCHEMBL8773331 | 0.71 | OPRM1 (0.35) | MAOBMAOA | |
| SCHEMBL13379626 | 0.68 | CA12 (0.48) | — | |
| SCHEMBL70588 | 0.66 | ALDH1A1 (0.38) | MAOBMAOAHSD11B1 | |
| SCHEMBL10893354 | 0.65 | OPRM1 (0.34) | MAOBMAOA | |
| SCHEMBL27698499 | 0.65 | OPRM1 (0.31) | MAOBMAOA | |
| SCHEMBL5906264 | 0.63 | TLR9 (0.40) | GAAMAOBMAOAAKR1C1 | |
| SCHEMBL7169778 | 0.63 | MAPT (0.36) | MAOBMAOAHTT | |
| SCHEMBL8992355 | 0.62 | MAOB (0.38) | GAAMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6566428-B1 | Stress cracking resistance, notched impact strength and heat resistance | BAYER AKTIENGESELLSCHAFT (DE) | 2003-05-20 | — | — | US | disclosed |