Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI1 | Q9ULC6 | 5/20 | 0.55 |
| ▸ | PADI4 | Q9UM07 | 5/20 | 0.55 |
| ▸ | PADI2 | Q9Y2J8 | 4/20 | 0.55 |
| ▸ | PDE4A | P27815 | 3/20 | 0.55 |
| ▸ | PADI3 | Q9ULW8 | 3/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.55 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.55 |
| ▸ | PADI6 | Q6TGC4 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | HPGDS | O60760 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7199412 | 0.99 | PADI1 (0.54) | PADI1PADI4PADI2PDE4APADI3 | |
| SCHEMBL28281357 | 0.81 | HPGDS (0.67) | PADI1PADI4PADI2PDE4APADI3 | |
| SCHEMBL2569798 | 0.81 | HPGDS (0.67) | PADI1PADI4PADI2PDE4APADI3 | |
| SCHEMBL4181143 | 0.78 | PADI1 (0.62) | PADI1PADI4PADI2PDE4APADI3 | |
| SCHEMBL18395838 | 0.76 | PADI1 (0.57) | PADI1PADI4PADI2PDE4APADI3 | |
| SCHEMBL28108803 | 0.75 | HPGDS (0.69) | PADI1PADI4PADI2PDE4APADI3 | |
| SCHEMBL10518630 | 0.75 | HPGDS (0.69) | PADI1PADI4PADI2PDE4APADI3 | |
| SCHEMBL158990 | 0.74 | PADI1 (0.60) | PADI1PADI4PADI2PDE4APADI3 | |
| SCHEMBL10946109 | 0.74 | PADI1 (0.60) | PADI1PADI4PADI2PDE4APADI3 | |
| SCHEMBL13697775 | 0.73 | HPGDS (0.71) | PADI1PADI4PADI2PDE4APADI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6555584-B1 | Acetyl-coa carboxylase inhibitors | AJINOMOTO CO., INC. (JP) | 2003-04-29 | — | — | US | disclosed |