Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | AGXT | P21549 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18650069 | 0.88 | TSHR (0.43) | TSHRIDO1MAPTKMT2AKDM4E | |
| SCHEMBL5929542 | 0.84 | TSHR (0.46) | MAOBTSHRAPPIDO1MAPT | |
| SCHEMBL11743736 | 0.84 | TSHR (0.46) | MAOBTSHRAPPIDO1MAPT | |
| SCHEMBL28165157 | 0.82 | TSHR (0.44) | MAOBTSHRAPPIDO1MAPT | |
| SCHEMBL11770115 | 0.82 | CA4 (0.39) | TSHRALDH1A1LMNAPTGS1SLC6A3 | |
| SCHEMBL2353448 | 0.82 | CA4 (0.39) | TSHRALDH1A1LMNAPTGS1SLC6A3 | |
| SCHEMBL9407989 | 0.81 | MAOB (0.43) | MAOBTSHRAPPIDO1MAPT | |
| SCHEMBL1856299 | 0.74 | LTA4H (0.45) | TSHRALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL7934188 | 0.73 | TSHR (0.52) | MAOBTSHRAPPIDO1MAPT | |
| SCHEMBL194803 | 0.73 | TSHR (0.57) | MAOBTSHRAPPIDO1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268644-A1 | SYNERGISTIC STABILIZER COMPOSITIONS FOR THERMOPLASTIC POLYMERS IN PROLONGED CONTACT WITH WATER | Clariant Finance (BVI) Limited (VG) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001062840-A1 | SYNERGISTIC STABILIZER COMPOSITIONS FOR THERMOPLASTIC POLYMERS IN PROLONGED CONTACT WITH WATER | CLARIANT INTERNATIONAL LTD (CH) | 2001-08-30 | — | — | WO | disclosed |