Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | CTSB | P07858 | 2/20 | 0.45 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | CTSV | O60911 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | CTSC | P53634 | 1/20 | 0.45 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16194624 | 1.00 | CTSL (0.45) | CTSLCTSBCTSKCTSVCTSS | |
| SCHEMBL17079965 | 1.00 | CTSL (0.45) | CTSLCTSBCTSKCTSVCTSS | |
| SCHEMBL16195504 | 1.00 | CTSL (0.45) | CTSLCTSBCTSKCTSVCTSS | |
| SCHEMBL10303684 | 1.00 | CTSL (0.45) | CTSLCTSBCTSKCTSVCTSS | |
| SCHEMBL17079964 | 1.00 | CTSL (0.45) | CTSLCTSBCTSKCTSVCTSS | |
| SCHEMBL17086951 | 1.00 | CTSL (0.45) | CTSLCTSBCTSKCTSVCTSS | |
| SCHEMBL18384827 | 1.00 | CTSL (0.45) | CTSLCTSBCTSKCTSVCTSS | |
| SCHEMBL16195226 | 1.00 | CTSL (0.45) | CTSLCTSBCTSKCTSVCTSS | |
| SCHEMBL20404231 | 1.00 | CTSL (0.45) | CTSLCTSBCTSKCTSVCTSS | |
| SCHEMBL19985774 | 1.00 | CTSL (0.45) | CTSLCTSBCTSKCTSVCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4626423-A1 | CDK INHIBITORS AND METHODS AND USE THEREOF | Relay Therapeutics, Inc. (US) | 2025-10-08 | — | — | EP | disclosed |
| WO-2024119122-A1 | CDK INHIBITORS AND METHODS AND USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2024-06-06 | — | — | WO | disclosed |
| EP-3504176-B1 | DIFLUORINATED COMPOUNDS AS DEPIGMENTING OR LIGHTENING AGENTS | TFCHEM (FR) | 2020-06-17 | — | — | EP | disclosed |
| US-10640441-B2 | Difluorinated compounds as depigmenting or lightening agents | TFCHEM (FR) | 2020-05-05 | — | — | US | disclosed |
| US-20190322608-A1 | DIFLUORINATED COMPOUNDS AS DEPIGMENTING OR LIGHTENING AGENTS | TFCHEM (FR) | 2019-10-24 | — | — | US | disclosed |
| US-9937186-B2 | Sulfonamides derived from tricyclyl-2-aminocycloalkanols as anticancer agents | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2018-04-10 | — | — | US | disclosed |
| WO-2018037254-A1 | DIFLUORINATED COMPOUNDS AS DEPIGMENTING OR LIGHTENING AGENTS | TFCHEM (FR) | 2018-03-01 | — | — | WO | disclosed |
| WO-2018037086-A1 | DIFLUORINATED COMPOUNDS AS DEPIGMENTING OR LIGHTENING AGENTS | TFCHEM (FR) | 2018-03-01 | — | — | WO | disclosed |
| EP-3116860-B1 | SULFONAMIDES DERIVED FROM TRICYCLYL-2-AMINOCYCLOALKANOLS AS ANTICANCER AGENTS | ICAHN SCHOOL MED MOUNT SINAI (US) | 2018-02-07 | — | — | EP | disclosed |
| WO-2017044572-A1 | RING CONSTRAINED DIARYLAMINO SULFONAMIDES AS ANTI-CANCER AGENTS | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2017-03-16 | — | — | WO | disclosed |
| US-20170015625-A1 | SULFONAMIDES DERIVED FROM TRICYCLYL-2-AMINOCYCLOALKANOLS AS ANTICANCER AGENTS | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2017-01-19 | — | — | US | disclosed |
| EP-3116860-A1 | SULFONAMIDES DERIVED FROM TRICYCLYL-2-AMINOCYCLOALKANOLS AS ANTICANCER AGENTS | Icahn School of Medicine at Mount Sinai (US) | 2017-01-18 | — | — | EP | disclosed |
| EP-2813491-B1 | CYCLOALKANE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2016-11-02 | — | — | EP | disclosed |
| WO-2015138500-A1 | SULFONAMIDES DERIVED FROM TRICYCLYL-2-AMINOCYCLOALKANOLS AS ANTICANCER AGENTS | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2015-09-17 | — | — | WO | disclosed |
| JP-2003171211-A | 2-BENZYLOXY-7-OXABICYCLO[4.1.0]HEPTANE DERIVATIVE AND AGROCHEMICAL, ESPECIALLY HERBICIDE COMPRISING THE SAME | KUMIAI CHEM IND CO LTD | 2003-06-17 | — | — | JP | disclosed |
| WO-2001016125-A1 | 2-BENZYLOXY-7-OXABICYCLO[4.1.0]HEPTANE DERIVATIVES AND HERBICIDE CONTAINING THE SAME | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2001-03-08 | — | — | WO | disclosed |
| EP-0976707-A1 | CYCLOALKYL BENZYL ETHER COMPOUNDS | Nissan Chemical Industries, Ltd. (JP) | 2000-02-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190322608-A1 | DIFLUORINATED COMPOUNDS AS DEPIGMENTING OR LIGHTENING AGENTS | TYR, MITF, MC1R | CTSL 4574/4885CTSB 1495/4885CTSK 1348/4885 |
| US-20170015625-A1 | SULFONAMIDES DERIVED FROM TRICYCLYL-2-AMINOCYCLOALKANOLS AS ANTICANCER AGENTS | FOXO1, SKP2, FOXK1 | CTSL 3073/4885CTSB 3428/4885CTSK 2517/4885 |
| US-10640441-B2 | Difluorinated compounds as depigmenting or lightening agents | TYR, MITF, MC1R | CTSL 4574/4885CTSB 1495/4885CTSK 1348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.