Hydrochloric Acid

Hydrochloric Acid

SCHEMBL7201160

CN(C)c1ccc2c(c1[Zr+2]C1=CC=CC1)Cc1ccccc1-2.[Cl-].[Cl-]

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.33
PNMT P11086 1/20 0.31
DRD2 P14416 1/20 0.31
DRD4 P21917 1/20 0.31
DRD3 P35462 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7201177 0.86
Hydrochloric Acid SCHEMBL816276 0.82 PNMT (0.33) PGRPNMTDRD2DRD4DRD3
Hydrochloric Acid SCHEMBL27637603 0.82 KDR (0.33) PGRPNMTDRD2DRD4DRD3
Hydrochloric Acid SCHEMBL2484389 0.82 PNMT (0.33) PGRPNMTDRD2DRD4DRD3
Hydrochloric Acid SCHEMBL2481590 0.82 PNMT (0.33) PGRPNMTDRD2DRD4DRD3
Hydrochloric Acid SCHEMBL7193185 0.81 KDM4E (0.41) PNMTDRD2DRD4DRD3NPC1
Hydrochloric Acid SCHEMBL7195315 0.80 MAP3K9 (0.31)
Hydrochloric Acid SCHEMBL8670986 0.77 PNMT (0.34) PNMTDRD2DRD4DRD3
Hydrochloric Acid SCHEMBL646564 0.77 PNMT (0.39) PGRPNMTDRD2DRD4DRD3
Hydrochloric Acid SCHEMBL29556447 0.75 PGR (0.34) PGRPNMTDRD2DRD4DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240166774-A1 METHOD FOR PREPARING SUPPORTED OLEFIN POLYMERIZATION CATALYST, RESULTING CATALYST AND APPLICATION THEREOF ZHEJIANG UNIVERSITY (CN) 2024-05-23 US disclosed
EP-4273177-A1 METHOD FOR PREPARING SUPPORTED OLEFIN POLYMERIZATION CATALYST, RESULTING CATALYST AND APPLICATION THEREOF Zhejiang University (CN) 2023-11-08 EP disclosed
EP-0942006-B1 Catalyst for olefin polymer production and process for olefin polymer production employing the catalyst TOSOH CORP (JP) 2003-06-04 EP disclosed