Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 7/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 7/20 | 0.43 |
| ▸ | CALCRL | Q16602 | 3/20 | 0.41 |
| ▸ | CTSD | P07339 | 7/20 | 0.40 |
| ▸ | CTSE | P14091 | 7/20 | 0.40 |
| ▸ | BACE1 | P56817 | 4/20 | 0.40 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7195991 | 0.87 | CALCRL (0.46) | ITGB1ITGA4CALCRLCTSDCTSE | |
| SCHEMBL8334047 | 0.81 | CALCRL (0.49) | ITGB1ITGA4CALCRLCTSDCTSE | |
| SCHEMBL5208748 | 0.80 | CTSD (0.49) | ITGB1ITGA4CALCRLCTSDCTSE | |
| SCHEMBL1223367 | 0.77 | ITGB1 (0.64) | ITGB1ITGA4 | |
| SCHEMBL13035172 | 0.76 | ITGB1 (0.63) | ITGB1ITGA4 | |
| SCHEMBL7202828 | 0.76 | ITGB1 (0.41) | ITGB1ITGA4 | |
| SCHEMBL7197725 | 0.74 | ITGB1 (0.41) | ITGB1ITGA4CTSDBACE1 | |
| SCHEMBL7197381 | 0.74 | ITGB1 (0.41) | ITGB1ITGA4CTSDBACE1 | |
| SCHEMBL2045662 | 0.73 | REN (0.54) | CTSDCTSEBACE1 | |
| SCHEMBL7419554 | 0.73 | REN (0.54) | CTSDCTSEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596687-B1 | For treatment of many inflammatory and autoimmune diseases | BIOGEN, INC. | 2003-07-22 | — | — | US | claimed |