Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 3/20 | 0.54 |
| ▸ | NMUR2 | Q9GZQ4 | 4/20 | 0.50 |
| ▸ | NMUR1 | Q9HB89 | 3/20 | 0.50 |
| ▸ | CTSD | P07339 | 2/20 | 0.50 |
| ▸ | ACE | P12821 | 5/20 | 0.49 |
| ▸ | CTSE | P14091 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2045662 | 1.00 | REN (0.54) | RENNMUR2NMUR1CTSDACE | |
| SCHEMBL7411063 | 0.93 | ACE (0.56) | RENNMUR2ACEACE2 | |
| SCHEMBL8060131 | 0.93 | ACE (0.56) | RENNMUR2ACEACE2 | |
| SCHEMBL8334047 | 0.91 | CALCRL (0.49) | RENNMUR2CTSDCTSEBACE1 | |
| SCHEMBL6374240 | 0.89 | OPRM1 (0.52) | ACEACE2 | |
| SCHEMBL27499487 | 0.85 | REN (0.49) | RENNMUR2NMUR1CTSDACE | |
| SCHEMBL5208748 | 0.84 | CTSD (0.49) | CTSDACECTSEBACE1ACE2 | |
| SCHEMBL7414240 | 0.83 | ACE (0.49) | RENCTSDACECTSEBACE1 | |
| SCHEMBL30788009 | 0.81 | NMUR2 (0.53) | NMUR2NMUR1ACEACE2 | |
| SCHEMBL8330748 | 0.81 | ACE (0.60) | ACEBACE1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000002903-A1 | CS-1 PEPTIDOMIMETICS, COMPOSITIONS AND METHODS OF USING THE SAME | CYTEL CORPORATION (US) | 2000-01-20 | — | — | WO | disclosed |
| EP-0737204-A4 | CS-1 PEPTIDOMIMETICS, COMPOSITIONS AND METHODS OF USING THE SAME | CYTEL CORP (US) | 1999-06-23 | — | — | EP | disclosed |
| EP-0737204-A1 | CS-1 PEPTIDOMIMETICS, COMPOSITIONS AND METHODS OF USING THE SAME | CYTEL CORPORATION (US) | 1996-10-16 | — | — | EP | disclosed |
| WO-1995015973-A1 | CS-1 PEPTIDOMIMETICS, COMPOSITIONS AND METHODS OF USING THE SAME | CYTEL CORPORATION (US) | 1995-06-15 | — | — | WO | disclosed |