Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | PGK1 | P00558 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | PLEC | Q15149 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14113095 | 0.88 | TSHR (0.47) | TSHRCYP3A4RECQLPGK1ALDH1A1 | |
| SCHEMBL27851120 | 0.77 | RECQL (0.44) | TSHRCYP3A4RECQLPGK1ALDH1A1 | |
| SCHEMBL3789681 | 0.73 | SMN1; SMN2 (0.44) | TSHRCYP3A4RECQLALDH1A1IDO1 | |
| SCHEMBL27900428 | 0.72 | CYP3A4 (0.40) | TSHRCYP3A4RECQLALDH1A1IDO1 | |
| SCHEMBL27857255 | 0.72 | LMNA (0.41) | TSHRCYP3A4RECQLALDH1A1IDO1 | |
| SCHEMBL7201523 | 0.71 | HSD17B10 (0.54) | TSHRCYP3A4RECQLALDH1A1HSD17B10 | |
| SCHEMBL3398998 | 0.71 | MEN1 (0.50) | TSHRIDO1GAAHTTLMNA | |
| SCHEMBL9750778 | 0.70 | CYP3A4 (0.50) | TSHRCYP3A4RECQLPGK1ALDH1A1 | |
| SCHEMBL12895731 | 0.70 | ALDH1A1 (0.40) | TSHRCYP3A4RECQLALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL6518247 | 0.70 | MEN1 (0.48) | TSHRIDO1GAAHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101942087-B | Metal ion-hyperbranched polyamidoamine complex catalyst and application thereof in preparation of polyphenyl ether in aqueous medium | UNIV ZHEJIANG | 2012-05-09 | — | — | CN | disclosed |