Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.48 |
| ▸ | HTR1D | P28221 | 6/20 | 0.47 |
| ▸ | HTR1B | P28222 | 6/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 4/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9357232 | 0.88 | HTR1D (0.52) | HTR1AHTR1DHTR1BMTNR1AMTNR1B | |
| Oxalic Acid SCHEMBL7513247 | 0.86 | HTR1A (0.47) | HTR1AHTR1DHTR1BMTNR1AMTNR1B | |
| Bromide SCHEMBL7513869 | 0.86 | HTR1A (0.49) | HTR1AHTR1DHTR1BMTNR1AMTNR1B | |
| SCHEMBL8890771 | 0.83 | HTR1D (0.47) | HTR1AHTR1DHTR1BMTNR1AMTNR1B | |
| SCHEMBL8891553 | 0.81 | HTR1A (0.49) | HTR1AHTR1DHTR1BMTNR1AMTNR1B | |
| SCHEMBL7208815 | 0.78 | HTR1A (0.78) | HTR1AHTR1DHTR1BDRD2 | |
| SCHEMBL7204648 | 0.78 | HTR1A (0.78) | HTR1AHTR1DHTR1BDRD2 | |
| SCHEMBL7516393 | 0.77 | HTR1A (0.49) | HTR1AHTR1DHTR1BMTNR1AMTNR1B | |
| SCHEMBL9532979 | 0.76 | MTNR1A (0.64) | HTR1DHTR1BMTNR1AMTNR1BDRD2 | |
| Phosphoric Acid SCHEMBL7509101 | 0.74 | HTR1A (0.46) | HTR1AHTR1DHTR1BMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471576-B1 | 6-substituted-tetrahydrobenz[cd]indoles | LILLY CO ELI (US) | 2003-03-12 | — | — | EP | claimed |
| US-5229409-A | Antidepressant, tranquilizer | ELI LILLY AND COMPANY (US) | 1993-07-20 | — | — | US | claimed |
| EP-0471576-B1 | 6-substituted-tetrahydrobenz[cd]indoles | LILLY CO ELI (US) | 2003-03-12 | — | — | EP | disclosed |
| US-5229409-A | Antidepressant, tranquilizer | ELI LILLY AND COMPANY (US) | 1993-07-20 | — | — | US | disclosed |