Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 6/20 | 0.52 |
| ▸ | HTR1B | P28222 | 6/20 | 0.52 |
| ▸ | HTR1A | P08908 | 3/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891553 | 0.93 | HTR1A (0.49) | HTR1DHTR1BHTR1AMTNR1AMTNR1B | |
| Oxalic Acid SCHEMBL7513247 | 0.89 | HTR1A (0.47) | HTR1DHTR1BHTR1AMTNR1AMTNR1B | |
| Bromide SCHEMBL7513869 | 0.89 | HTR1A (0.49) | HTR1DHTR1BHTR1AMTNR1AMTNR1B | |
| SCHEMBL8890771 | 0.88 | HTR1D (0.47) | HTR1DHTR1BHTR1AMTNR1AMTNR1B | |
| SCHEMBL7201548 | 0.88 | HTR1A (0.48) | HTR1DHTR1BHTR1AMTNR1AMTNR1B | |
| SCHEMBL8891420 | 0.84 | MTNR1A (0.52) | HTR1DHTR1BHTR1AMTNR1AMTNR1B | |
| SCHEMBL7516393 | 0.80 | HTR1A (0.49) | HTR1DHTR1BHTR1AMTNR1AMTNR1B | |
| SCHEMBL8891187 | 0.79 | HTR1A (0.45) | HTR1DHTR1BHTR1AMTNR1AMTNR1B | |
| SCHEMBL9532979 | 0.79 | MTNR1A (0.64) | HTR1DHTR1BMTNR1AMTNR1BDRD2 | |
| SCHEMBL8889776 | 0.77 | HTR1A (0.83) | HTR1DHTR1BHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0392768-B1 | Tetrahydrobenz[C,D] indole serotonin agonists | LILLY CO ELI (US) | 1994-12-07 | — | — | EP | disclosed |