Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22994872 | 0.87 | SLC6A2 (0.43) | LMNAAOC3GRIN1GRIN2AGRIN2D | |
| SCHEMBL19337210 | 0.86 | MGLL (0.36) | LMNAAOC3GRIN1GRIN2AGRIN2D | |
| SCHEMBL6880285 | 0.86 | TSHR (0.47) | LMNAAOC3GRIN1GRIN2AGRIN2D | |
| SCHEMBL19336907 | 0.86 | MGLL (0.36) | LMNAAOC3GRIN1GRIN2AGRIN2D | |
| SCHEMBL18383113 | 0.86 | AOC3 (0.40) | LMNAAOC3GRIN1GRIN2AGRIN2D | |
| SCHEMBL95074 | 0.79 | TSHR (0.42) | LMNAGRIN1GRIN2AGRIN2DGRIN2C | |
| SCHEMBL39602 | 0.75 | ALDH1A1 (0.36) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B | |
| SCHEMBL6887995 | 0.73 | ALDH1A1 (0.35) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B | |
| Aniline SCHEMBL4439642 | 0.71 | ALDH1A1 (0.45) | AOC3GRIN1GRIN2AGRIN2DGRIN2C | |
| SCHEMBL6880364 | 0.71 | TSHR (0.41) | LMNAAOC3GRIN1GRIN2AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8329625-B2 | Aqueous functional fluids with antioxidants | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2012-12-11 | — | — | US | disclosed |
| EP-0728806-B2 | Synergistic stabiliser mixture | CIBA SC HOLDING AG (CH) | 2003-05-14 | — | — | EP | disclosed |