Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | FOS | P01100 | 2/20 | 0.42 |
| ▸ | JUN | P05412 | 2/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 9/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7193702 | 0.93 | NPC1 (0.48) | NPC1PKMRAB9AFOSJUN | |
| SCHEMBL7195014 | 0.89 | NPC1 (0.40) | NPC1PKMRAB9AFOSJUN | |
| SCHEMBL7197674 | 0.86 | FOS (0.54) | NPC1PKMRAB9AFOSJUN | |
| SCHEMBL7191896 | 0.85 | FOS (0.43) | NPC1PKMRAB9AFOSJUN | |
| SCHEMBL7195073 | 0.84 | FOS (0.53) | FOSJUNABCB1 | |
| SCHEMBL7196642 | 0.84 | NPC1 (0.45) | NPC1PKMRAB9A | |
| SCHEMBL7198863 | 0.82 | FOS (0.40) | NPC1PKMRAB9AFOSJUN | |
| SCHEMBL7191795 | 0.82 | NPC1 (0.43) | NPC1PKMRAB9A | |
| SCHEMBL7196658 | 0.81 | THRA (0.46) | NPC1PKMRAB9A | |
| SCHEMBL7198353 | 0.80 | THRA (0.47) | NPC1PKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030065039-A1 | Biologically active 1,3-bis-aromatic-prop-2-en-1-ones, 1,3-bis-aromatic-propan-1-ones, and 1,3-bis-aromatic-prop-2-yn-1-ones | STATENS SERUM INSTITUTE (DK) | 2003-04-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065039-A1 | Biologically active 1,3-bis-aromatic-prop-2-en-1-ones, 1,3-bis-aromatic-propan-1-ones, and 1,3-bis-aromatic-prop-2-yn-1-ones | AKR1C3, AKR1C1, AKR1A1 | NPC1 3105/4885PKM 749/4885RAB9A 3774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.