SCHEMBL72017

SCHEMBL72017

O=C(Oc1ccccc1)c1cccc2c1C(=O)c1cccc(C(=O)Oc3ccccc3)c1C2=O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 7/20 0.59
▸ L3MBTL1 Q9Y468 1/20 0.59
▸ MAPT P10636 5/20 0.57
▸ KDM4E B2RXH2 2/20 0.57
▸ TDP1 Q9NUW8 1/20 0.57
▸ HSD17B10 Q99714 2/20 0.56
▸ HPGD P15428 1/20 0.56
▸ ALOX15 P16050 1/20 0.56
▸ LMNA P02545 4/20 0.54
▸ NPC1 O15118 1/20 0.54
▸ TSHR P16473 1/20 0.48
▸ KMT2A Q03164 1/20 0.48
▸ CYP1A2 P05177 1/20 0.47
▸ CYP2C9 P11712 1/20 0.47
▸ CYP2C19 P33261 1/20 0.47
▸ THRB P10828 1/20 0.45
▸ KEAP1 Q14145 1/20 0.45
▸ NFE2L2 Q16236 1/20 0.45
▸ NPSR1 Q6W5P4 1/20 0.44
▸ NR4A2 P43354 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6762145 0.95 ALDH1A1 (0.57) ALDH1A1L3MBTL1MAPTKDM4ETDP1
SCHEMBL28376689 0.81 MAPT (0.56) ALDH1A1MAPTKDM4ETDP1HSD17B10
SCHEMBL69537 0.81 HSD17B10 (0.68) ALDH1A1MAPTKDM4ETDP1HSD17B10
SCHEMBL28137661 0.81 KDM4E (0.55) ALDH1A1L3MBTL1MAPTKDM4ETDP1
SCHEMBL8040042 0.80 ALDH1A1 (0.60) ALDH1A1L3MBTL1MAPTKDM4ETDP1
SCHEMBL69868 0.79 HSD17B10 (0.76) ALDH1A1L3MBTL1MAPTKDM4ETDP1
SCHEMBL29437924 0.79 HSD17B10 (0.76) ALDH1A1L3MBTL1MAPTKDM4ETDP1
SCHEMBL2386152 0.79 ALDH1A1 (0.68) ALDH1A1L3MBTL1MAPTTDP1LMNA
SCHEMBL9306956 0.78 HNF4A (0.64) ALDH1A1MAPTKDM4ETDP1HSD17B10
Hydrogen Sulfide SCHEMBL28157119 0.77 HSD17B10 (0.73) ALDH1A1L3MBTL1MAPTKDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 — — EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 — — US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 — — US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 — — US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 ALDH1A1 1882/4885L3MBTL1 4274/4885MAPT 1923/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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