Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 14/20 | 0.64 |
| ▸ | HTR1D | P28221 | 14/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27478384 | 1.00 | HTR1A (0.64) | HTR1AHTR1DCA2 | |
| SCHEMBL8970632 | 0.85 | HTR1A (0.64) | HTR1AHTR1DCA2 | |
| SCHEMBL8052654 | 0.83 | HTR1A (0.66) | HTR1AHTR1DCA2 | |
| SCHEMBL8864373 | 0.83 | HTR1A (0.66) | HTR1AHTR1DCA2 | |
| SCHEMBL27471154 | 0.82 | HTR1A (0.60) | HTR1AHTR1DCA2 | |
| SCHEMBL8879867 | 0.82 | HTR1A (0.60) | HTR1AHTR1DCA2 | |
| SCHEMBL8049371 | 0.82 | HTR1A (0.60) | HTR1AHTR1DCA2 | |
| SCHEMBL5723599 | 0.81 | HTR1A (0.67) | HTR1AHTR1DCA2 | |
| SCHEMBL7309998 | 0.79 | HTR1A (0.57) | HTR1AHTR1DCA2 | |
| SCHEMBL8864160 | 0.79 | DRD2 (0.72) | HTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714396-B1 | VASOCONTRICTIVE DIHYDROBENZOPYRAN DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2003-12-10 | — | — | EP | claimed |
| CN-1052006-C | Dihydrobenzopyran derivatives as vasoconstrictors, preparation and use thereof | JANSSEN PHARMACEUTICA NV (NL) | 2000-05-03 | — | — | CN | claimed |
| CN-1129451-A | Dihydrobenzopyran derivatives as vasoconstrictors | JANSSEN PHARMACEUTICA NV (BE) | 1996-08-21 | — | — | CN | claimed |
| CN-1155597-C | Benzodioxan, benzofuran or benzopyranl derivatives having fundic relaxation properties | ղɭҩҵ����˾ | 2004-06-30 | — | — | CN | disclosed |
| EP-0714396-B1 | VASOCONTRICTIVE DIHYDROBENZOPYRAN DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2003-12-10 | — | — | EP | disclosed |
| CN-1280577-A | Benzodioxan, benzofuran or benzopyranl derivatives having fundic relaxation properties | JANSSEN PHARMACEUTICA NV (BE) | 2001-01-17 | — | — | CN | disclosed |
| CN-1052006-C | Dihydrobenzopyran derivatives as vasoconstrictors, preparation and use thereof | JANSSEN PHARMACEUTICA NV (NL) | 2000-05-03 | — | — | CN | disclosed |
| CN-1129451-A | Dihydrobenzopyran derivatives as vasoconstrictors | JANSSEN PHARMACEUTICA NV (BE) | 1996-08-21 | — | — | CN | disclosed |