Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 8/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 9/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7202561 | 0.92 | ALOX15 (0.50) | MDM2ALOX15 | |
| SCHEMBL7206121 | 0.90 | ALOX15 (0.48) | MDM2ALOX15 | |
| SCHEMBL7205778 | 0.89 | ALOX15 (0.47) | MDM2ALOX15 | |
| SCHEMBL7206116 | 0.89 | ALOX15 (0.54) | MDM2ALOX15 | |
| SCHEMBL7205430 | 0.89 | ALOX15 (0.53) | MDM2ALOX15ALDH1A1CYP1A2HPGD | |
| Water SCHEMBL27532088 | 0.88 | ALOX15 (0.52) | MDM2ALOX15ALDH1A1CYP1A2HPGD | |
| SCHEMBL7203969 | 0.87 | ALOX15 (0.44) | MDM2ALOX15 | |
| SCHEMBL7203970 | 0.86 | ALOX15 (0.53) | ALOX15 | |
| SCHEMBL7205567 | 0.86 | ALDH1A1 (0.42) | MDM2ALOX15ALDH1A1CYP1A2HPGD | |
| SCHEMBL7203961 | 0.85 | ALDH1A1 (0.50) | ALOX15ALDH1A1CYP1A2HPGDXBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6608070-B1 | Useful for treatment of medical condition in which prostaglandins are implicated as pathogens | NAKAO KAZUNARI (JP) | 2003-08-19 | — | — | US | disclosed |