Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 12/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7208485 | 0.89 | ALOX15 (0.47) | ALOX15MCL1MDM2 | |
| SCHEMBL7202561 | 0.89 | ALOX15 (0.50) | ALOX15MDM2 | |
| SCHEMBL7202043 | 0.87 | MDM2 (0.48) | ALOX15MDM2 | |
| SCHEMBL7202805 | 0.87 | ALOX15 (0.42) | ALOX15MCL1MDM2 | |
| SCHEMBL7206121 | 0.87 | ALOX15 (0.48) | ALOX15MDM2 | |
| SCHEMBL7205778 | 0.86 | ALOX15 (0.47) | ALOX15MDM2 | |
| SCHEMBL6171989 | 0.86 | SRD5A2 (0.43) | MCL1 | |
| SCHEMBL7205430 | 0.86 | ALOX15 (0.53) | ALOX15MDM2 | |
| Water SCHEMBL27532088 | 0.85 | ALOX15 (0.52) | ALOX15MDM2 | |
| SCHEMBL7203970 | 0.84 | ALOX15 (0.53) | ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6608070-B1 | Useful for treatment of medical condition in which prostaglandins are implicated as pathogens | NAKAO KAZUNARI (JP) | 2003-08-19 | — | — | US | disclosed |