Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | FLI1 | Q01543 | 1/20 | 0.40 |
| ▸ | EWSR1 | Q01844 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL457696 | 0.85 | HAO1 (0.44) | HAO1PLK1MMP2MMP9MMP8 | |
| SCHEMBL396689 | 0.84 | PTPN1 (0.48) | ALDH1A1SMN1; SMN2MAPK1GAAMEN1 | |
| SCHEMBL4032443 | 0.79 | PLOD2 (0.64) | HAO1PLK1MMP2MMP9MMP8 | |
| SCHEMBL20202561 | 0.79 | GSK3B (0.55) | ALDH1A1SMN1; SMN2GAAMEN1LMNA | |
| SCHEMBL21758947 | 0.77 | EPHX2 (0.49) | HAO1PLK1MMP2MMP9MMP8 | |
| SCHEMBL5312596 | 0.77 | HAO1 (0.46) | HAO1PLK1MMP2MMP9MMP8 | |
| SCHEMBL275400 | 0.76 | HAO1 (0.56) | HAO1PLK1MMP2MMP9MMP8 | |
| SCHEMBL6302968 | 0.76 | HAO1 (0.56) | HAO1PLK1MMP2MMP9MMP8 | |
| SCHEMBL2074862 | 0.76 | PLOD2 (0.60) | SMN1; SMN2MEN1MAPTRAB9AKMT2A | |
| SCHEMBL28729892 | 0.76 | RAB9A (0.58) | ALDH1A1SMN1; SMN2MAPK1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596445-B1 | Initiators for photopolymerization of radically polymerizable compounds | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-07-22 | — | — | US | disclosed |