SCHEMBL7202407

SCHEMBL7202407

CCNc1cc(NCC)nnn1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRG2 P18507 2/20 0.40
GABRB3 P28472 2/20 0.40
GABRA5 P31644 2/20 0.40
GABRA3 P34903 2/20 0.40
GABRA1 P14867 1/20 0.40
EGFR P00533 1/20 0.36
HCAR3 P49019 1/20 0.34
KCNH2 Q12809 2/20 0.33
CACNA1C Q13936 2/20 0.33
SCN5A Q14524 2/20 0.33
PGK1 P00558 2/20 0.33
ADRA2A P08913 1/20 0.32
ADRA2B P18089 1/20 0.32
ADRA2C P18825 1/20 0.32
PIK3CD O00329 1/20 0.32
PIP5K1C O60331 1/20 0.32
PIK3CA P42336 1/20 0.32
PIK3CB P42338 1/20 0.32
PI4KA P42356 1/20 0.32
PIK3CG P48736 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28209553 0.84 GABRG2 (0.35) GABRG2GABRB3GABRA5GABRA3GABRA1
SCHEMBL17210140 0.74 EGFR (0.56) EGFRHCAR3ADRA2AADRA2BADRA2C
SCHEMBL5845138 0.72
SCHEMBL12895620 0.70 GABRG2 (0.49) GABRG2GABRB3GABRA5GABRA3GABRA1
SCHEMBL11916242 0.70 GABRG2 (0.49) GABRG2GABRB3GABRA5GABRA3GABRA1
SCHEMBL11689561 0.70 ESR1 (0.61) EGFRKCNH2CACNA1CSCN5APGK1
SCHEMBL12518240 0.67 HCAR3 (0.50) GABRG2GABRB3GABRA5GABRA3GABRA1
SCHEMBL25986701 0.66 GABRG2 (0.45) GABRG2GABRB3GABRA5GABRA3GABRA1
SCHEMBL11916247 0.66 GABRG2 (0.45) GABRG2GABRB3GABRA5GABRA3GABRA1
SCHEMBL25715326 0.66 GABRG2 (0.45) GABRG2GABRB3GABRA5GABRA3GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024197286-A1 A METHOD OF USING SIMAZINE FOR CONTROLLING ANNUAL BLUEGRASS IN COOL-SEASON TURFGRASSES HOWARD HAROLD F (US) 2024-09-26 WO disclosed
WO-2003050094-A1 REACTIVE LIQUID POLYMER CROSSLINKING AGENT AND PROCESS FOR PREPARATION LCB WORLDWIDE INC. (US) 2003-06-19 WO disclosed