Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7205397 | 0.95 | REN (0.49) | REN | |
| SCHEMBL9182734 | 0.89 | HDAC3 (0.50) | — | |
| SCHEMBL22633373 | 0.89 | KCNH2 (0.44) | — | |
| SCHEMBL7206733 | 0.87 | MAOA (0.53) | — | |
| SCHEMBL17508108 | 0.86 | MAOA (0.54) | — | |
| SCHEMBL3666097 | 0.84 | MAOA (0.52) | — | |
| SCHEMBL17527067 | 0.84 | MAOA (0.52) | — | |
| SCHEMBL17527074 | 0.84 | MAOA (0.52) | — | |
| SCHEMBL16390835 | 0.84 | MAOA (0.52) | — | |
| SCHEMBL7202171 | 0.84 | MAOA (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6605645-B2 | Such as 1,15-di(cyclopropylmethylamino)-8-benzyl-4,8,12-triazapentadecane; carcinostatic action | RIKEN (JP) | 2003-08-12 | — | — | US | disclosed |
| US-20020067472-A1 | Linear polyamine compounds and polyamine anticancer agents | IWATA MASAAKI (JP) | 2002-06-06 | — | — | US | disclosed |
| US-6319956-B1 | N1, N4-BIS(CYCLOPROPYLMETHYLAMINO)TRIALKYLENETETRAMINES THAT MAY BE TOLUENESULFONATED. | RIKEN (JP) | 2001-11-20 | — | — | US | disclosed |