Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | PPIA | P62937 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9811775 | 0.85 | ALDH1A1 (0.62) | NPC1ALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL27393236 | 0.85 | NPC1 (0.62) | NPC1ALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL28761254 | 0.85 | ALDH1A1 (0.73) | NPC1ALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL10772687 | 0.85 | CES2 (0.57) | NPC1ALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL21313818 | 0.82 | ALDH1A1 (0.69) | NPC1ALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL9782243 | 0.80 | ALDH1A1 (0.67) | NPC1ALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL994062 | 0.79 | GAA (0.64) | NPC1ALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL7160814 | 0.79 | CYP3A4 (0.53) | NPC1ALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL6450415 | 0.79 | ALDH1A1 (0.70) | NPC1ALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL27675594 | 0.78 | KMT2A (0.48) | NPC1ALDH1A1HPGDMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117958270-A | Pesticide for preventing and treating bakanae disease and damping-off of rice | 江西省农业科学院植物保护研究所 | 2024-05-03 | — | — | CN | claimed |
| CN-104302287-B | Indolin-2-one derivatives as protein kinase inhibitors | 安基生技新药股份有限公司 | 2017-12-26 | — | — | CN | claimed |
| EP-2838531-B1 | INDOLIN-2-ONE DERIVATIVES AS PROTEIN KINASE INHIBITORS | ANNJI PHARM CO LTD (CN) | 2016-09-21 | — | — | EP | claimed |
| US-8946282-B2 | Indolin-2-one derivatives as protein kinase inhibitors | Annji Pharmaceutical Co., Ltd. (TW) | 2015-02-03 | — | — | US | claimed |
| CN-104302287-A | Indolin-2-one derivatives as protein kinase inhibitors | ANNJI PHARM CO LTD | 2015-01-21 | — | — | CN | claimed |
| US-20130281451-A1 | INDOLIN-2-ONE DERIVATIVES AS PROTEIN KINASE INHIBITORS | Annji Pharmaceutical Co., Ltd. (TW) | 2013-10-24 | — | — | US | claimed |
| EP-0242322-B1 | PHENYLUREAS | SANDOZ AG (CH) | 1992-12-16 | — | — | EP | claimed |
| EP-0118392-B1 | N-BENZOYL UREAS AND THEIR USE AS PESTICIDES | CIBA-GEIGY AG (CH) | 1987-08-12 | — | — | EP | claimed |
| CN-118217268-A | Aquatic insecticide containing hexaflumuron and application thereof | 湖南坤源生物科技有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-115677523-B | Preparation method of 2, 6-difluorobenzamide | 江苏新河农用化工有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-117958270-A | Pesticide for preventing and treating bakanae disease and damping-off of rice | 江西省农业科学院植物保护研究所 | 2024-05-03 | — | — | CN | disclosed |
| CN-117958270-A | Pesticide for preventing and treating bakanae disease and damping-off of rice | 江西省农业科学院植物保护研究所 | 2024-05-03 | — | — | CN | disclosed |
| CN-117919215-A | Aquatic insecticide containing lufenuron and application thereof | 湖南坤源生物科技有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-117024270-A | Preparation method of 2, 4-difluoro-3, 5-dichlorobenzoyl fluoride | 浙江中欣氟材股份有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-1225626-A | 2-chloro-3, 5-bis (trifluoromethyl) phenylbenzoyl urea derivatives and preparation method thereof | HANWHA CORP (KR) | 1999-08-11 | — | — | CN | disclosed |
| US-4992544-A | Intermediates for b-lactam antibiotics and b-lactamase inhibitor | UNIVERSITY OF NOTRE DAME DU LAC (US) | 1991-02-12 | — | — | US | disclosed |
| EP-0248765-A2 | Novel benzoylureas | SANDOZ AG (CH) | 1987-12-09 | — | — | EP | disclosed |
| CN-85109721-A | Preparation has the ectoparasite of the no disease homoiothermic animal of control and the method for endoparasite compositions | — | 1987-07-15 | — | — | CN | disclosed |
| CN-86102098-A | The preparation technology of 1-(4-Phenoxyphenyl)-3-benzoyl urea compound | — | 1986-10-15 | — | — | CN | disclosed |
| CN-86100630-A | Preparation contains the method for the sterilant of acylurea | — | 1986-09-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281451-A1 | INDOLIN-2-ONE DERIVATIVES AS PROTEIN KINASE INHIBITORS | ING2, CDK2, MAP3K20 | NPC1 3108/4885ALDH1A1 3369/4885HPGD 1319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.