SCHEMBL994062

SCHEMBL994062

NNC(=O)c1ccccc1F

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.64
MEN1 O00255 2/20 0.62
KMT2A Q03164 2/20 0.62
TDP1 Q9NUW8 1/20 0.62
ALDH1A1 P00352 3/20 0.60
NPC1 O15118 3/20 0.60
MAPT P10636 2/20 0.60
HPGD P15428 2/20 0.60
ALOX15 P16050 1/20 0.59
CES2 O00748 1/20 0.58
CES1 P23141 1/20 0.58
LMNA P02545 1/20 0.56
RAB9A P51151 2/20 0.56
CTSD P07339 2/20 0.53
PTPN1 P18031 1/20 0.53
ERCC5 P28715 1/20 0.53
FEN1 P39748 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA9 Q16790 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL30746017 0.98 GAA (0.62) GAAMEN1KMT2ATDP1ALDH1A1
Hydrochloric Acid SCHEMBL30605742 0.98 GAA (0.62) GAAMEN1KMT2ATDP1ALDH1A1
SCHEMBL30547074 0.84 CTSD (0.63) GAAMEN1KMT2ATDP1ALDH1A1
SCHEMBL239328 0.84 CTSD (0.63) GAAMEN1KMT2ATDP1ALDH1A1
SCHEMBL4033535 0.83 MEN1 (0.68) MEN1KMT2ATDP1NPC1MAPT
SCHEMBL29970839 0.83 CES2 (0.56) GAAMEN1KMT2ATDP1ALDH1A1
SCHEMBL2646708 0.83 CES2 (0.61) GAAMEN1KMT2ATDP1ALDH1A1
SCHEMBL6450415 0.82 ALDH1A1 (0.70) GAAMEN1KMT2ATDP1ALDH1A1
Hydrochloric Acid SCHEMBL6692325 0.81 CTSD (0.61) GAAMEN1KMT2ATDP1ALDH1A1
Hydrazine SCHEMBL14300720 0.81 CTSD (0.61) GAAMEN1KMT2ATDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 378 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4688828-A1 RADIOPHARMACEUTICAL CONJUGATE COMPOUND FOR DIAGNOSIS AND/OR THERAPEUTIC USES THEREOF Jubilant DraxImage Inc. (CA) 2026-02-11 EP claimed
WO-2024201255-A1 RADIOPHARMACEUTICAL CONJUGATE COMPOUND FOR DIAGNOSIS AND/OR THERAPEUTIC USES THEREOF JUBILANT DRAXIMAGE INC. (CA) 2024-10-03 WO claimed
US-20240316226-A1 RADIOPHARMACEUTICAL CONJUGATE COMPOUND FOR DIAGNOSIS AND/OR THERAPEUTIC USES THEREOF JUBILANT DRAXIMAGE INC. (CA) 2024-09-26 US claimed
US-11398630-B2 Method of generating energy from a hydrazide containing anode fuel, and fuel cell IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2022-07-26 US claimed
CN-110041226-B Compound with AIE characteristics and preparation method and application thereof 江苏萨瑞斯医疗科技有限公司 2022-05-31 CN claimed
US-20210005900-A1 METHOD OF GENERATING ENERGY FROM A HYDRAZIDE CONTAINING ANODE FUEL, AND FUEL CELL IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2021-01-07 US claimed
CN-110041226-A Compound and its preparation method and application with AIE characteristic 江苏萨瑞斯医疗科技有限公司 2019-07-23 CN claimed
CN-106397420-B 3- (5- aryl-1,3,4-oxdiazole -2- bases) asarinin analog derivative, preparation method and application 郑州大学 2018-10-09 CN claimed
US-10040741-B2 Method for manufacturing high purity glycol based compound SAMSUNG DISPLAY CO., LTD. (KR) 2018-08-07 US claimed
CN-105669551-B 7 benzo (c) acridines are to fluorobenzoyl amido thiocarbamide and its preparation method and application 广西中医药大学 2018-04-17 CN claimed
CN-106397420-A 3-(5-aryl-1,3-4-oxadiazole-2-yl)sarisan derivatives, and preparation method and application thereof 郑州大学 2017-02-15 CN claimed
US-20160297732-A1 METHOD FOR MANUFACTURING HIGH PURITY GLYCOL BASED COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2016-10-13 US claimed
CN-103483300-B Preparation method of 5-cyanogen-1-(4-fluobenzene)-1,3-dihydrogenated-isobenzofuranone UNIV SOUTHEAST 2015-05-06 CN claimed
CN-104327043-A Acridinethioether-typed derivative, preparation method and application thereof UNIV GUANGXI CHINESE MEDICINE 2015-02-04 CN claimed
CN-102229576-B Method for synthesizing 1,2,4-triazine compound by using micro-reactor FUDAN UNIVERSITY (CN) 2014-10-29 CN claimed
CN-103130766-B Piperine hydrazone or acylhydrazone or sulfonyl hydrazone derivative substances and application for preparing a botanical insecticide UNIV NORTHWEST A&F 2014-06-11 CN claimed
CN-103483300-A Preparation method of 5-cyanogen-1-(4-fluobenzene)-1,3-dihydrogenated-isobenzofuranone UNIV SOUTHEAST 2014-01-01 CN claimed
CN-103130766-A Piperine hydrazone or acylhydrazone or sulfonyl hydrazone derivative substances and application for preparing a botanical insecticide UNIV NORTHWEST A&F 2013-06-05 CN claimed
CN-102690258-A Nitrogenous heterocyclic-imide derivative and preparation method and purpose thereof HUBEI BIOPESTICIDE ENGINEERING RES CT 2012-09-26 CN claimed
EP-3829559-B1 INHIBITORS OF HISTONE DEACETYLASE USEFUL FOR THE TREATMENT OR PREVENTION OF HIV INFECTION MERCK SHARP & DOHME LLC (US) 2026-05-13 EP disclosed
US-12612409-B2 Pyrrolopyrimidines as CFTR potentiators CYSTIC FIBROSIS FOUNDATION (US) 2026-04-28 US disclosed
EP-4688828-A1 RADIOPHARMACEUTICAL CONJUGATE COMPOUND FOR DIAGNOSIS AND/OR THERAPEUTIC USES THEREOF Jubilant DraxImage Inc. (CA) 2026-02-11 EP disclosed
US-12539339-B2 Radiopharmaceutical conjugate compound for diagnosis and/or therapeutic uses thereof JUBILANT DRAXIMAGE INC. (IN) 2026-02-03 US disclosed
WO-2025264954-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS ALEXION PHARMACEUTICALS, INC. (US) 2025-12-26 WO disclosed
US-12338243-B2 P2X7 modulators JANSSEN PHARMACEUTICA NV (BE) 2025-06-24 US disclosed
US-12331044-B2 Inhibitors of histone deacetylase useful for the treatment or prevention of HIV infection MERCK SHARP & DOHME LLC (US) 2025-06-17 US disclosed
WO-2024206895-A1 PYRAZOLO-PYRIMIDINE COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS RECTIFY PHARMACEUTICALS, INC. (US) 2024-10-03 WO disclosed
WO-2024201255-A1 RADIOPHARMACEUTICAL CONJUGATE COMPOUND FOR DIAGNOSIS AND/OR THERAPEUTIC USES THEREOF JUBILANT DRAXIMAGE INC. (CA) 2024-10-03 WO disclosed
US-20240316226-A1 RADIOPHARMACEUTICAL CONJUGATE COMPOUND FOR DIAGNOSIS AND/OR THERAPEUTIC USES THEREOF JUBILANT DRAXIMAGE INC. (CA) 2024-09-26 US disclosed
US-20240300932-A1 N-PHENYLIMINE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF GUIZHOU UNIVERSITY (CN) 2024-09-12 US disclosed
CN-114466850-B [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine 拜耳股份有限公司 2024-09-10 CN disclosed
EP-4424311-A2 PYRROLOPYRIMIDINES AS CFTR POTENTIATORS Cystic Fibrosis Foundation (US) 2024-09-04 EP disclosed
WO-2024174317-A1 N-PHENYLIMINE-CONTAINING DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF 贵州大学 2024-08-29 WO disclosed
CN-118026948-A Tri-aromatic ring compound and preparation method, pharmaceutical composition and application thereof 中国药科大学 2024-05-14 CN disclosed
EP-3541390-B1 PYRROLOPYRIMIDINES AS CFTR POTENTIATORS CYSTIC FIBROSIS FOUND (US) 2024-05-01 EP disclosed
CN-117024375-A Preparation method and application of thiadiazole histone deacetylase inhibitor compound 济南大学 2023-11-10 CN disclosed
CN-116887827-A Compounds and methods for modulating FXR 拓臻制药公司 2023-10-13 CN disclosed
US-11731934-B2 HDAC inhibitor compounds and methods of treatment UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2023-08-22 US disclosed
US-20230250100-A1 Pyrrolopyrimidines as CFTR Potentiators CYSTIC FIBROSIS FOUNDATION THERAPEUTICS INC. 2023-08-10 US disclosed
WO-2023097386-A1 SELECTIVE HDAC6-INHIBITING N-ACYLHYDRAZONE COMPOUNDS, METHODS FOR PRODUCING SAME, COMPOSITIONS, USES, TREATMENT METHODS AND KITS EUROFARMA LABORATÓRIOS S.A (BR) 2023-06-08 WO disclosed
WO-2023097386-A1 SELECTIVE HDAC6-INHIBITING N-ACYLHYDRAZONE COMPOUNDS, METHODS FOR PRODUCING SAME, COMPOSITIONS, USES, TREATMENT METHODS AND KITS EUROFARMA LABORATÓRIOS S.A (BR) 2023-06-08 WO disclosed
CN-111165475-B Hydrogel as carrier for active ingredient and method for preparing the same 温菲尔德解决方案公司 2023-05-26 CN disclosed
US-11634391-B2 Compounds which are inhibitors of Notum UCL BUSINESS LTD (GB) 2023-04-25 US disclosed
US-20230113037-A1 [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES BAYER AKTIENGESELLSCHAFT (DE) 2023-04-13 US disclosed
CN-115850268-A Pyrrolopyrimidines as CFTR potentiators 囊性纤维化基金会 2023-03-28 CN disclosed
US-20230030414-A1 COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE VERTEX PHARMACEUTICALS INCORPORATED 2023-02-02 US disclosed
CN-110337294-B Pyrrolopyrimidines as CFTR potentiators 囊性纤维化基金会 2022-11-01 CN disclosed
EP-4059932-A1 COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE Vertex Pharmaceuticals Incorporated (US) 2022-09-21 EP disclosed
WO-2022180080-A1 ANTI-PROLIFERATIVE AGENTS FIRST HEALTH PHARMACEUTICALS B.V. (NL) 2022-09-01 WO disclosed
EP-4050002-A1 ANTI-PROLIFERATIVE AGENTS First Health Pharmaceuticals B.V. (NL) 2022-08-31 EP disclosed
US-20220235062-A1 P2X7 MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2022-07-28 US disclosed
US-11398630-B2 Method of generating energy from a hydrazide containing anode fuel, and fuel cell IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2022-07-26 US disclosed
EP-4013508-A1 [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES Bayer Aktiengesellschaft (DE) 2022-06-22 EP disclosed
CN-110041226-B Compound with AIE characteristics and preparation method and application thereof 江苏萨瑞斯医疗科技有限公司 2022-05-31 CN disclosed
CN-114466850-A [1,2,4] triazolo [1,5-C ] quinazolin-5-amines 拜耳股份有限公司 2022-05-10 CN disclosed
WO-2022086284-A1 PROTEIN KINASE INHIBITOR AND USE THEREOF (주)메디톡스 2022-04-28 WO disclosed
WO-2022035763-A1 BORON CONTAINING COMPOUNDS AND THEIR USES 5METIS, INC. (US) 2022-02-17 WO disclosed
EP-3354650-B1 COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE VERTEX PHARMA (US) 2022-02-16 EP disclosed
US-11149040-B2 Fused triazole agonists of the APJ receptor AMGEN INC. (US) 2021-10-19 US disclosed
US-20210276992-A1 INHIBITORS OF HISTONE DEACETYLASE USEFUL FOR THE TREATMENT OR PREVENTION OF HIV INFECTION MERCK SHARP & DOHME CORP. (US) 2021-09-09 US disclosed
US-20210276992-A1 INHIBITORS OF HISTONE DEACETYLASE USEFUL FOR THE TREATMENT OR PREVENTION OF HIV INFECTION MERCK SHARP & DOHME CORP. (US) 2021-09-09 US disclosed
EP-3843844-A1 COMPOUNDS UCL Business Ltd (GB) 2021-07-07 EP disclosed
US-20210171475-A1 COMPOUNDS UCL BUSINESS LTD (GB) 2021-06-10 US disclosed
US-20210171534-A1 Pyrrolopyrimidines as CFTR Potentiators CYSTIC FIBROSIS FOUNDATION 2021-06-10 US disclosed
EP-3829559-A1 INHIBITORS OF HISTONE DEACETYLASE USEFUL FOR THE TREATMENT OR PREVENTION OF HIV INFECTION Merck Sharp & Dohme Corp. (US) 2021-06-09 EP disclosed
CN-110846675-B Synthetic method of 2- (5-aryl-1, 3, 4-oxadiazole-2-yl) aniline compound 阜阳师范大学 2021-05-28 CN disclosed
CN-111057065-B Preparation method and application of thienopyrimidine compound 沈阳药科大学 2021-04-23 CN disclosed
US-10961232-B2 Substituted pyrazines as ATR kinase inhibitors VERTEX PHARMACEUTICALS INCORPORATED (US) 2021-03-30 US disclosed
WO-2021028382-A1 [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES BAYER AKTIENGESELLSCHAFT (DE) 2021-02-18 WO disclosed
US-10906890-B2 Triazole phenyl compounds as agonists of the APJ receptor AMGEN INC. (US) 2021-02-02 US disclosed
US-20210009509-A1 HDAC INHIBITOR COMPOUNDS AND METHODS OF TREATMENT UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2021-01-14 US disclosed
US-20210005900-A1 METHOD OF GENERATING ENERGY FROM A HYDRAZIDE CONTAINING ANODE FUEL, AND FUEL CELL IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2021-01-07 US disclosed
WO-2020264581-A1 BORON CONTAINING COMPOUNDS AND THEIR USES Boragen, Inc. (US) 2020-12-30 WO disclosed
EP-3541810-B1 TRIAZOLE PHENYL COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR AMGEN INC (US) 2020-12-23 EP disclosed
US-10807944-B2 HDAC inhibitor compounds and methods of treatment UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2020-10-20 US disclosed
US-20200308189-A1 FUSED TRIAZOLE AGONISTS OF THE APJ RECEPTOR AMGEN INC. (US) 2020-10-01 US disclosed
CN-109705045-B Pyrimidine antitumor compound and preparation method and application thereof 中国医科大学 2020-07-14 CN disclosed
CN-106496209-B Compounds useful as inhibitors of ATR kinase 沃泰克斯药物股份有限公司 2020-06-30 CN disclosed
CN-106496210-B Compounds useful as inhibitors of ATR kinase 沃泰克斯药物股份有限公司 2020-06-09 CN disclosed
CN-111107846-A Heteroaryl allosteric modulators of nicotinic acetylcholine receptors 默沙东公司 2020-05-05 CN disclosed
CN-106518856-B Compounds useful as inhibitors of ATR kinase 沃泰克斯药物股份有限公司 2020-04-28 CN disclosed
CN-111057065-A Preparation method and application of thienopyrimidine compound 沈阳药科大学 2020-04-24 CN disclosed
WO-2020043866-A1 COMPOUNDS UCL BUSINESS LTD (GB) 2020-03-05 WO disclosed
CN-110846675-A Synthetic method of 2- (5-aryl-1, 3, 4-oxadiazole-2-yl) aniline compound 阜阳师范大学 2020-02-28 CN disclosed
WO-2020028150-A1 INHIBITORS OF HISTONE DEACETYLASE USEFUL FOR THE TREATMENT OR PREVENTION OF HIV INFECTION MERCK SHARP & DOHME CORP. (US) 2020-02-06 WO disclosed
WO-2020028150-A1 INHIBITORS OF HISTONE DEACETYLASE USEFUL FOR THE TREATMENT OR PREVENTION OF HIV INFECTION MERCK SHARP & DOHME CORP. (US) 2020-02-06 WO disclosed
US-20200017512-A1 PYRROLOPYRIMIDINES AS CFTR POTENTIATORS PFIZER INC. 2020-01-16 US disclosed
US-10479784-B2 Substituted pyrazin-2-amines as inhibitors of ATR kinase VERTEX PHARMACEUTICALS INCORPORATED (US) 2019-11-19 US disclosed
CN-110337294-A Pyrrolopyrimidines as CFTR potentiators 囊性纤维化基金会治疗公司 2019-10-15 CN disclosed
EP-3541390-A1 PYRROLOPYRIMIDINES AS CFTR POTENTIATORS Cystic Fibrosis Foundation Therapeutics Inc. (US) 2019-09-25 EP disclosed
US-20190284173-A1 TRIAZOLE PHENYL COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR AMGEN INC. (US) 2019-09-19 US disclosed
EP-3191488-B1 P2X7 MODULATING N-ACYL-TRIAZOLOPYRAZINES JANSSEN PHARMACEUTICA NV (BE) 2019-08-14 EP disclosed
US-20190225621-A1 PYRROLOPYRIMIDINES AS CFTR POTENTIATORS CYSTIC FIBROSIS FOUNDATION 2019-07-25 US disclosed
EP-3215505-B1 PIPERIDINYLPYRAZOLOPYRIMIDINONES AND THEIR USE Bayer Pharma AG (DE) 2019-07-24 EP disclosed
CN-110041226-A Compound and its preparation method and application with AIE characteristic 江苏萨瑞斯医疗科技有限公司 2019-07-23 CN disclosed
US-10301315-B2 Pyrrolopyrimidines as CFTR potentiators CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. (US) 2019-05-28 US disclosed
CN-106146487-B Pyridylmethyl dithiocarbonic acid hetero-aromatic ring alkyl esters compound and its preparation method and application 北京大学 2019-05-10 CN disclosed
US-20190047995-A1 COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE VERTEX PHARMACEUTICALS INCORPORATED 2019-02-14 US disclosed
US-10118930-B2 Piperidinylpyrazolopyrimidinones and their use BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2018-11-06 US disclosed
CN-106397420-B 3- (5- aryl-1,3,4-oxdiazole -2- bases) asarinin analog derivative, preparation method and application 郑州大学 2018-10-09 CN disclosed
US-10040741-B2 Method for manufacturing high purity glycol based compound SAMSUNG DISPLAY CO., LTD. (KR) 2018-08-07 US disclosed
EP-3354650-A1 COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE Vertex Pharmaceuticals Incorporated (US) 2018-08-01 EP disclosed
CN-108218848-A A kind of trifluoromethyl pyridine oxadiazoles(Ether)Analog derivative and its application 贵州大学 2018-06-29 CN disclosed
US-20180170922-A1 COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE VERTEX PHARMACEUTICALS INCORPORATED 2018-06-21 US disclosed
US-20180141954-A1 PYRROLOPYRIMIDINES AS CFTR POTENTIATORS CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. (US) 2018-05-24 US disclosed
WO-2018094137-A1 PYRROLOPYRIMIDINES AS CFTR POTENTIATORS CYSTIC FIBROSIS FOUNDATION THERAPEUTICS INC. (US) 2018-05-24 WO disclosed
US-20180118749-A1 P2X7 MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2018-05-03 US disclosed
CN-105330651-B 1 containing (miscellaneous) aryl and piperazine, 2,4- triazolinthione derivatives and preparation method and application 南开大学 2018-05-01 CN disclosed
CN-105669551-B 7 benzo (c) acridines are to fluorobenzoyl amido thiocarbamide and its preparation method and application 广西中医药大学 2018-04-17 CN disclosed
CN-104892590-B Benzheterocycle substitutes 1,3,4 oxadiazole class compounds and its preparation method and application 华东师范大学 2018-03-06 CN disclosed
EP-2376485-B1 PYRAZINE DERIVATIVES USEFUL AS INHIBITORS OF ATR KINASE VERTEX PHARMA (US) 2017-12-06 EP disclosed
US-20170334917-A1 PIPERIDINYLPYRAZOLOPYRIMIDINONES AND THEIR USE BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2017-11-23 US disclosed
EP-3215505-A1 PIPERIDINYLPYRAZOLOPYRIMIDINONES AND THEIR USE Bayer Pharma Aktiengesellschaft (DE) 2017-09-13 EP disclosed
CN-105541748-B 1,3,4 oxadiazole Mannich base class compounds and preparation and application containing piperazine 南开大学 2017-09-12 CN disclosed
CN-104488901-B A kind of complex composition and preparation of the azoles of bacterium containing methylsulfonyl and antibioticses bactericide 广西田园生化股份有限公司 2017-09-05 CN disclosed
CN-104488904-B A kind of complex composition of the azoles of bacterium containing methylsulfonyl and benzimidazole germicide 广西田园生化股份有限公司 2017-09-05 CN disclosed
CN-104488897-B The complex composition and preparation of the azoles of bacterium containing methylsulfonyl and carbamate fungicide 广西田园生化股份有限公司 2017-09-05 CN disclosed
CN-104488900-B A kind of complex composition of the azoles of bacterium containing methylsulfonyl and anabasine insecticide 广西田园生化股份有限公司 2017-09-05 CN disclosed
CN-104488902-B The azoles of bacterium containing methylsulfonyl and miazines or the complex composition of quinoline series bactericidal agent 广西田园生化股份有限公司 2017-09-05 CN disclosed
CN-104488893-B A kind of complex composition and preparation of the azoles of bacterium containing methylsulfonyl and plant growth regulator 广西田园生化股份有限公司 2017-09-05 CN disclosed
CN-104488930-B A kind of complex composition and preparation of the azoles of bacterium containing methylsulfonyl and Zhongshengmycin 广西田园生化股份有限公司 2017-09-05 CN disclosed
CN-107108638-A Piperidyl PyrazolopyrimidinonecGMP and application thereof 拜耳制药股份公司 2017-08-29 CN disclosed
EP-3191488-A1 P2X7 MODULATING N-ACYL-TRIAZOLOPYRAZINES Janssen Pharmaceutica, N.V. (BE) 2017-07-19 EP disclosed
US-9701674-B2 Substituted pyrazines as ATR kinase inhibitors VERTEX PHARMACEUTICALS INCORPORATED (US) 2017-07-11 US disclosed
US-20170174619-A1 HDAC INHIBITOR COMPOUNDS AND METHODS OF TREATMENT UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2017-06-22 US disclosed
CN-106866708-A 1,2,4 triazols [3,4 b] 1,3,4 thiadiazole compounds and its application 天津理工大学 2017-06-20 CN disclosed
CN-104488963-B Compound composition with methanesulphonyl myclobutanil and organic copper bactericide and preparation 广西田园生化股份有限公司 2017-04-19 CN disclosed
CN-104542629-B The complex composition and preparation of a kind of azoles of bacterium containing methylsulfonyl and Inorganic Copper series bactericidal agent 广西田园生化股份有限公司 2017-04-05 CN disclosed
CN-104542628-B The complex composition and preparation of a kind of azoles of bacterium containing methylsulfonyl and Thiodiazole-copper 广西田园生化股份有限公司 2017-03-29 CN disclosed
CN-106518856-A Pyrazine derivatives useful as inhibitors of ATR kinase 沃泰克斯药物股份有限公司 2017-03-22 CN disclosed
CN-106496209-A It is used as the compound of ATR kinase inhibitors 沃泰克斯药物股份有限公司 2017-03-15 CN disclosed
CN-106496210-A It is used as the compound of ATR kinase inhibitors 沃泰克斯药物股份有限公司 2017-03-15 CN disclosed
CN-104542627-B Compound composition containing methanesulfonyl bacteria oxazole and morpholine fungicides and preparation 广西田园生化股份有限公司 2017-02-22 CN disclosed
CN-106397420-A 3-(5-aryl-1,3-4-oxadiazole-2-yl)sarisan derivatives, and preparation method and application thereof 郑州大学 2017-02-15 CN disclosed
CN-104672162-B Preparation method and use of pentadiene ketone compound containing 1,3,4-oxadiazole sulfo-ethyoxyl 贵州大学 2017-01-25 CN disclosed
CN-104542625-B Compound composition containing methanesulfonyl bacteria oxazole and oxazole bactericide and preparation 广西田园生化股份有限公司 2017-01-11 CN disclosed
CN-104521991-B A kind of containing methylsulfonyl bacterium azoles and the complex composition of chlorobromide isocyanuric acid and preparation 广西田园生化股份有限公司 2017-01-04 CN disclosed
CN-104327043-B A kind of acridine thioether analog derivative and its production and use GUANGXI UNIVERSITY OF CHINESE MEDICINE (CN) 2017-01-04 CN disclosed
CN-102300862-B Compounds useful as inhibitors of ATR kinase 沃泰克斯药物股份有限公司 2016-11-23 CN disclosed
CN-106146487-A Pyridylmethyl dithiocarbonic acid hetero-aromatic ring alkyl esters compound and its production and use 北京大学 2016-11-23 CN disclosed
CN-106132958-A Pyridine 2 amides compound as CB2 agonist 豪夫迈·罗氏有限公司 2016-11-16 CN disclosed
US-20160311809-A1 COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE VERTEX PHARMACEUTICALS INCORPORATED (US) 2016-10-27 US disclosed
US-20160297732-A1 METHOD FOR MANUFACTURING HIGH PURITY GLYCOL BASED COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2016-10-13 US disclosed
CN-104488926-B A kind of containing methylsulfonyl bacterium azoles and the complex composition of thifluzamide and preparation 广西田园生化股份有限公司 2016-10-05 CN disclosed
CN-104488907-B A kind of containing methylsulfonyl bacterium azoles and the complex composition of prothioconazoles and antibacterial 广西田园生化股份有限公司 2016-10-05 CN disclosed
CN-104522030-B A kind of containing methylsulfonyl bacterium azoles and the complex composition of imidazoles antibacterial and preparation 广西田园生化股份有限公司 2016-10-05 CN disclosed
CN-104488910-B Containing methylsulfonyl bacterium azoles and the complex composition of triazole bactericidal agent and preparation 广西田园生化股份有限公司 2016-10-05 CN disclosed
CN-104488906-B A kind of containing methylsulfonyl bacterium azoles and the complex composition of benziothiazolinone and antibacterial 广西田园生化股份有限公司 2016-10-05 CN disclosed
CN-105949181-A 4-hydroxyl pyrroline-2-ketone derivative containing 1,3,4-oxadiazole and preparation method and application of 4-hydroxyl pyrroline-2-ketone derivative 贵州大学 2016-09-21 CN disclosed
CN-104521992-B Containing methylsulfonyl bacterium azoles and the complex composition of dicarboximide series bactericidal agent and preparation 广西田园生化股份有限公司 2016-08-24 CN disclosed
CN-104488903-B A kind of containing methylsulfonyl bacterium azoles with the complex composition of the gloomy copper of thiophene 广西田园生化股份有限公司 2016-08-24 CN disclosed
CN-104542695-B A kind of containing methylsulfonyl bacterium azoles and the complex composition of toxic fluoride phosphate and preparation 广西田园生化股份有限公司 2016-08-24 CN disclosed
CN-104488899-B A kind of containing methylsulfonyl bacterium azoles and the complex composition of zinc thiazole and preparation 广西田园生化股份有限公司 2016-08-24 CN disclosed
CN-104585184-B A kind of complex composition containing methylsulfonyl bacterium azoles 广西田园生化股份有限公司 2016-08-24 CN disclosed
CN-104521988-B A kind of containing methylsulfonyl bacterium azoles and the complex composition of tiger glue adipic acid copper and preparation 广西田园生化股份有限公司 2016-08-24 CN disclosed
CN-104488905-B A kind of containing methylsulfonyl bacterium azoles and the complex composition of S-Ethyl ethylthio sulfonate and preparation 广西田园生化股份有限公司 2016-08-24 CN disclosed
CN-104488928-B Containing methylsulfonyl bacterium azoles and the complex composition of dithiocarbamate antibacterial and preparation 广西田园生化股份有限公司 2016-08-24 CN disclosed
CN-104621173-B A kind of composition pesticide containing methylsulfonyl bacterium azoles and preparation 广西田园生化股份有限公司 2016-08-24 CN disclosed
CN-104488896-B Containing methylsulfonyl bacterium azoles and the complex composition of methoxy acrylic bactericide and preparation 广西田园生化股份有限公司 2016-08-24 CN disclosed
CN-104488898-B Containing methylsulfonyl bacterium azoles and the complex composition of Xinjunan acetate and antibacterial 广西田园生化股份有限公司 2016-08-17 CN disclosed
CN-104488895-B A kind of containing methylsulfonyl bacterium azoles and the complex composition of sym-closene 广西田园生化股份有限公司 2016-08-17 CN disclosed
CN-104521990-B A kind of containing methylsulfonyl bacterium azoles and the complex composition of Flutriafol and antibacterial 广西田园生化股份有限公司 2016-08-17 CN disclosed
CN-104488894-B A kind of containing methylsulfonyl bacterium azoles and the complex composition of fluopicolide and antibacterial 广西田园生化股份有限公司 2016-08-17 CN disclosed
CN-104542626-B A kind of containing methylsulfonyl bacterium azoles and the complex composition of CGA-173506 and preparation 广西田园生化股份有限公司 2016-08-17 CN disclosed
CN-104488908-B A kind of containing methylsulfonyl bacterium azoles and the complex composition of Yekuzuo and preparation 广西田园生化股份有限公司 2016-08-17 CN disclosed
CN-104521989-B Containing methylsulfonyl bacterium azoles and the complex composition of acid amide fungicides and preparation 广西田园生化股份有限公司 2016-08-17 CN disclosed
CN-104542624-B A kind of complex composition containing methylsulfonyl bacterium azoles and preparation 广西田园生化股份有限公司 2016-07-27 CN disclosed
CN-104522035-B A kind of containing methylsulfonyl bacterium azoles and the complex composition of fenaminosulf and preparation 广西田园生化股份有限公司 2016-07-27 CN disclosed
CN-104521987-B A kind of containing methylsulfonyl bacterium azoles and the complex composition of amide-type insecticide and preparation 广西田园生化股份有限公司 2016-07-27 CN disclosed
CN-104488909-B A kind of complex composition containing methylsulfonyl bacterium azoles and Fluoxastrobin and preparation 广西田园生化股份有限公司 2016-07-06 CN disclosed
CN-104488911-B A kind of insecticidal and bactericidal composition containing methylsulfonyl bacterium azoles and preparation 广西田园生化股份有限公司 2016-06-29 CN disclosed
CN-105669551-A 7-benzo(c)acridine-p-fluorobenzamidothiourea, preparation method and application thereof 广西中医药大学 2016-06-15 CN disclosed
US-9365557-B2 Substituted pyrazin-2-amines as inhibitors of ATR kinase VERTEX PHARMACEUTICALS INCORPORATED (US) 2016-06-14 US disclosed
CN-104542693-B A kind of complex composition containing methylsulfonyl bacterium azoles and organophosphorus insecticides and preparation 广西田园生化股份有限公司 2016-06-08 CN disclosed
WO-2016071216-A1 PIPERIDINYLPYRAZOLOPYRIMIDINONES AND THEIR USE BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2016-05-12 WO disclosed
CN-105541748-A Piperazine-contained 1,3,4-oxadiazole Mannich base compound, and preparation and application thereof UNIV NANKAI 2016-05-04 CN disclosed
WO-2016039983-A1 P2X7 MODULATING N-ACYL-TRIAZOLOPYRAZINES JANSSEN PHARMACEUTICA NV (BE) 2016-03-17 WO disclosed
CN-105330651-A 1,2,4-Triazolethione derivative containing (hetero)aryl group and piperazine, and preparation method and application thereof UNIV NANKAI 2016-02-17 CN disclosed
CN-103275066-B 3,5-bis-replaces 4-aminotriazole compounds and synthetic method thereof and application NANJING NORMAL UNIVERSITY (CN) 2016-01-27 CN disclosed
CN-102690258-B Nitrogen heterocyclic ring imine derivative and its production and use HUBEI PROVINCE BIOLOGICAL PESTICIDE ENGINEERING RESEARCH CENTER (CN) 2015-11-25 CN disclosed
CN-105001241-A S-triazolo-thiadiazole and thiadiazine derivatives, preparation method and application thereof INST MED BIOTECHNOLOGY CAMS 2015-10-28 CN disclosed
WO-2015153516-A1 HDAC INHIBITOR COMPOUNDS AND METHODS OF TREATMENT UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) 2015-10-08 WO disclosed
CN-104892590-A Benzheterocycle substituted 1,3,4-oxadiazole compound, preparation method and applications thereof UNIV EAST CHINA NORMAL 2015-09-09 CN disclosed
CN-104744358-A Pyridine formylhydrazine compounds with insecticidal activity and preparation method and application thereof UNIV ZHEJIANG TECHNOLOGY 2015-07-01 CN disclosed
CN-104672162-A Preparation method and use of pentadiene ketone compound containing 1,3,4-oxadiazole sulfo-ethyoxyl UNIV GUIZHOU 2015-06-03 CN disclosed
CN-104621173-A Methanesulfonylipconazole-containing pesticide composition and preparation GAUNGXI TIANYUAN BIOCHEMISTRY 2015-05-20 CN disclosed
CN-103483300-B Preparation method of 5-cyanogen-1-(4-fluobenzene)-1,3-dihydrogenated-isobenzofuranone UNIV SOUTHEAST 2015-05-06 CN disclosed
CN-104585184-A Compound composition containing methanesulfonyl azole GAUNGXI TIANYUAN BIOCHEMISTRY 2015-05-06 CN disclosed
CN-104542627-A Compound composition containing methanesulfonyl bacteria oxazole and morpholine fungicides and preparation GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-29 CN disclosed
CN-104542625-A Compound composition containing methanesulfonyl bacteria oxazole and oxazole bactericide and preparation GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-29 CN disclosed
CN-104542695-A Bactericidal composition containing 2-p-fluorophenyl-5-methylsulfonyl-1,3,4-oxadiazole and Dufulin and preparation containing 2-p-fluorophenyl-5-methylsulfonyl-1,3,4-oxadiazole and Dufulin GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-29 CN disclosed
CN-104542693-A Compound composition containing methanesulfonyl bacteria oxazole and organophosphorus insecticides and preparation GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-29 CN disclosed
CN-104542628-A Compound composition containing 2-p-fluorophenyl-5-methylsulfonyl-1,3,4-oxadiazole and thiodiazole copper and preparation containing2-p-fluorophenyl-5-methylsulfonyl-1,3,4-oxadiazole and thiodiazole copper GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-29 CN disclosed
CN-104542626-A Compound composition containing methanesulfonyl bacteria oxazole and fludioxonil GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-29 CN disclosed
CN-104542624-A Compound composition containing methanesulfonyl bacteria oxazole and preparation GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-29 CN disclosed
CN-104542629-A Compound composition containing methanesulfonyl bacteria oxazole and inorganic copper fungicides and preparation GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-29 CN disclosed
CN-104521987-A 2-(p-fluorophenyl)-5-methanesulfonyl-1,3,4-oxadiazole and amide insecticide-containing compound composition and preparation GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-22 CN disclosed
CN-104521990-A Compound composition containing 2-(p-fluorophenyl)-5-methanesulfonyl-1,3,4-oxadiazole and flutriafol and bactericide GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-22 CN disclosed
CN-104521992-A Compound composition containing methanesulfonylconazole and dicarboxyl imide fungicide and preparation of compound composition GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-22 CN disclosed
CN-104522030-A Compound composition containing 2-(p-fluorophenyl)-5-methanesulfonyl-1,3,4-oxadiazole and imidazole bactericides and preparation GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-22 CN disclosed
CN-104521991-A Compound composition containing 2-(p-fluorophenyl)-5-methanesulfonyl-1,3,4-oxadiazole and chlorobromoisocyanuric acid and preparation GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-22 CN disclosed
CN-104521989-A Compound composition containing 2-(p-fluorophenyl)-5-methanesulfonyl-1,3,4-oxadiazole and amide bactericides and preparation GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-22 CN disclosed
CN-104522035-A Compound composition containing 2-(p-fluorophenyl)-5-methanesulfonyl-1,3,4-oxadiazole and leasn and preparation GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-22 CN disclosed
CN-104521988-A Compound composition containing 2-(p-fluorophenyl)-5-methanesulfonyl-1,3,4-oxadiazole and Copper(succinate+glutarate+adipate) and preparation GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-22 CN disclosed
CN-104488905-A Compound composition containing methanesulphonyl myclobutanil and ethylicin and preparation GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-08 CN disclosed
CN-104488900-A Compound composition containing methanesulphonyl myclobutanil and neonicotinoid insecticide GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-08 CN disclosed
CN-104488930-A Compound composition containing methanesulphonyl myclobutanil and zhongshengmycin and preparation GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-08 CN disclosed
CN-104488899-A Compound composition containing methanesulphonyl myclobutanil and zinc thiazole and preparation GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-08 CN disclosed
CN-104488894-A Compound composition containing methanesulphonyl myclobutanil and fluopicolide and bactericide GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-08 CN disclosed
CN-104488898-A Compound composition containing methylsulfonylconazole and xinjunan acetate and fungicide GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-08 CN disclosed
CN-104488928-A Compound composition containing methylsulfonylconazole and dithiocarbamate fungicide and preparation GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-08 CN disclosed
CN-104488909-A Compound composition and preparation containing methylsulfonyl azole and azoxystrobin GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-08 CN disclosed
CN-104488926-A Compound composition containing methanesulphonyl myclobutanil and thifluzamide and preparation GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-08 CN disclosed
CN-104488911-A Methylsulfonylconazole-containing insecticidal and bactericidal composition and preparation GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-08 CN disclosed
CN-104488896-A Compound composition containing methylsulfonylconazole and strobilurin fungicide and preparation GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-08 CN disclosed
CN-104488910-A Compound composition containing methylsulfonylconazole and triazole fungicide GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-08 CN disclosed
CN-104488895-A Compound composition containing methanesulphonyl myclobutanil and trichloroisocyanuric acid GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-08 CN disclosed
CN-104488963-A Compound composition with methanesulphonyl myclobutanil and organic copper bactericide and preparation GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-08 CN disclosed
CN-104488904-A Compound composition containing methanesulphonyl myclobutanil and benzimidazole bactericide GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-08 CN disclosed
CN-104488903-A Compound composition containing methanesulphonyl myclobutanil and saisentong GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-08 CN disclosed
CN-104488897-A Compound composition containing methanesulphonyl myclobutanil and carbamic acid ester bactericide and preparation GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-08 CN disclosed
CN-104488906-A Compound composition and bactericide containing methylsulfonyl azole and benziothiazolinone GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-08 CN disclosed
CN-104488901-A Compound composition containing methanesulphonyl myclobutanil and antibiotics bactericide and preparation GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-08 CN disclosed
CN-104488907-A Compound composition and bactericide containing methylsulfonyl azole and prothioconazole GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-08 CN disclosed
CN-104488902-A Compound composition containing methylsulfonylconazole and pyrimidine or quinoline fungicide GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-08 CN disclosed
CN-104496678-A Compound composition containing methanesulphonyl myclobutanil and leaf fertilizer and preparation GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-08 CN disclosed
CN-104488908-A Compound composition and preparation containing methylsulfonyl azole and bismerthiazol GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-08 CN disclosed
CN-104488893-A Compound composition containing methanesulphonyl myclobutanil and plant growth regulator and preparation GAUNGXI TIANYUAN BIOCHEMISTRY 2015-04-08 CN disclosed
US-8993570-B2 Substituted triazolo-pyridazine derivatives CONCERT PHARMACEUTICALS, INC. (US) 2015-03-31 US disclosed
US-8993570-B2 Substituted triazolo-pyridazine derivatives CONCERT PHARMACEUTICALS, INC. (US) 2015-03-31 US disclosed
US-8993570-B2 Substituted triazolo-pyridazine derivatives CONCERT PHARMACEUTICALS, INC. (US) 2015-03-31 US disclosed
US-20150051187-A1 COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE VERTEX PHARMACEUTICALS INCORPORATED 2015-02-19 US disclosed
CN-104327043-A Acridinethioether-typed derivative, preparation method and application thereof UNIV GUANGXI CHINESE MEDICINE 2015-02-04 CN disclosed
US-20150031661-A1 COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE VERTEX PHARMACEUTICALS INCORPORATED (US) 2015-01-29 US disclosed
CN-102766102-B Preparation method and application of fluorine-containing triazole compound UNIV ZHEJIANG TECHNOLOGY 2014-12-03 CN disclosed
CN-102229576-B Method for synthesizing 1,2,4-triazine compound by using micro-reactor FUDAN UNIVERSITY (CN) 2014-10-29 CN disclosed
CN-102399225-B 3-fluorine-containing substituted benzamido-3,4-dihydro-4-imide-5-methylthio-7-ethylthio pyrimido[4,5-d]pyrimidine with herbicidal activity and preparation method thereof UNIV JIANGXI NORMAL 2014-09-24 CN disclosed
US-8841308-B2 Pyrazin-2-amines useful as inhibitors of ATR kinase VERTEX PHARMACEUTICALS INCORPORATED (US) 2014-09-23 US disclosed
CN-101952275-B Modulators for amyloid protein beta HOFFMANN LA ROCHE 2014-06-18 CN disclosed
CN-103130766-B Piperine hydrazone or acylhydrazone or sulfonyl hydrazone derivative substances and application for preparing a botanical insecticide UNIV NORTHWEST A&F 2014-06-11 CN disclosed
EP-2282999-B1 AMINO-QUINOXALINE AND AMINO-QUINOLINE COMPOUNDS FOR USE AS ADENOSINE A2A RECEPTOR ANTAGONISTS MERCK SHARP & DOHME (US) 2014-05-21 EP disclosed
CN-103483300-A Preparation method of 5-cyanogen-1-(4-fluobenzene)-1,3-dihydrogenated-isobenzofuranone UNIV SOUTHEAST 2014-01-01 CN disclosed
US-20130317033-A1 SUBSTITUTED TRIAZOLO-PYRIDAZINE DERIVATIVES CONCERT PHARMACEUTICALS, INC. (US) 2013-11-28 US disclosed
CN-103275066-A 3, 5-disubstituted 4-aminotriazole compound, as well as preparation method and application thereof UNIV NANJING NORMAL 2013-09-04 CN disclosed
US-8501738-B2 Substituted triazolo-pyridazine derivatives CONCERT PHARMACEUTICALS, INC. (US) 2013-08-06 US disclosed
US-8501738-B2 Substituted triazolo-pyridazine derivatives CONCERT PHARMACEUTICALS, INC. (US) 2013-08-06 US disclosed
US-8501738-B2 Substituted triazolo-pyridazine derivatives CONCERT PHARMACEUTICALS, INC. (US) 2013-08-06 US disclosed
CN-103130766-A Piperine hydrazone or acylhydrazone or sulfonyl hydrazone derivative substances and application for preparing a botanical insecticide UNIV NORTHWEST A&F 2013-06-05 CN disclosed
US-8415353-B2 Amino-quinoxaline and amino-quinoline compounds for use as adenosine A2a receptor antagonists MERCK SHARP & DOHME CORP. (US) 2013-04-09 US disclosed
CN-101514176-B Compound N-fluorobenzamido-N'-phenylthiocarbamide as well as preparation and application thereof UNIV NORTHWEST NORMAL 2012-11-21 CN disclosed
CN-101514176-B Compound N-fluorobenzamido-N'-phenylthiocarbamide as well as preparation and application thereof UNIV NORTHWEST NORMAL 2012-11-21 CN disclosed
CN-102766102-A Preparation method and application of fluorine-containing triazole compound UNIV ZHEJIANG TECHNOLOGY 2012-11-07 CN disclosed
CN-102690258-A Nitrogenous heterocyclic-imide derivative and preparation method and purpose thereof HUBEI BIOPESTICIDE ENGINEERING RES CT 2012-09-26 CN disclosed
EP-2454259-A1 DEUTERIUM-MODIFIED TRIAZOLO-PYRIDAZINE DERIVATIVES AS GABA-A RECEPTOR MODULATORS Concert Pharmaceuticals Inc. (US) 2012-05-23 EP disclosed
CN-102300862-A Compounds useful as inhibitors of ATR kinase 2011-12-28 CN disclosed
CN-102229576-A Method for synthesizing 1,2,4-triazine compound by using micro-reactor UNIV FUDAN 2011-11-02 CN disclosed
EP-2376485-A1 PYRAZINE DERIVATIVES USEFUL AS INHIBITORS OF ATR KINASE Vertex Pharmaceuticals Incorporated (US) 2011-10-19 EP disclosed
CN-102216277-A Substituted benzamides as cannabinoid receptor ligands ABBOTT LAB 2011-10-12 CN disclosed
US-8013004-B2 Modulators of the glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof BRISTOL-MYERS SQUIBB COMPANY (US) 2011-09-06 US disclosed
US-7947683-B2 3-(1,2,4-triazol-3-ylalkyl) azabicyclo (3.1.0) hexane derivatives as modulators of dopamine D3 receptors GLAXO GROUP LIMTED (GB) 2011-05-24 US disclosed
US-20110105513-A1 AMINO-QUINOXALINE AND AMINO-QUINOLINE COMPOUNDS FOR USE AS ADENOSINE A2a RECEPTOR ANTAGONISTS MERCK SHARP & DOHME LLC 2011-05-05 US disclosed
US-20110065711-A1 SUBSTITUTED TRIAZOLO-PYRIDAZINE DERIVATIVES CONCERT PHARMACEUTICALS, INC. (US) 2011-03-17 US disclosed
US-20110065711-A1 SUBSTITUTED TRIAZOLO-PYRIDAZINE DERIVATIVES CONCERT PHARMACEUTICALS, INC. (US) 2011-03-17 US disclosed
US-20110065711-A1 SUBSTITUTED TRIAZOLO-PYRIDAZINE DERIVATIVES CONCERT PHARMACEUTICALS, INC. (US) 2011-03-17 US disclosed
EP-1836176-B1 MODULATORS OF THE GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-kB ACTIVITY AND USE THEROF BRISTOL MYERS SQUIBB CO (US) 2011-03-02 EP disclosed
EP-2282999-A1 AMINO-QUINOXALINE AND AMINO-QUINOLINE COMPOUNDS FOR USE AS ADENOSINE A2A RECEPTOR ANTAGONISTS Schering Corporation (US) 2011-02-16 EP disclosed
US-20110034472-A1 Novel Compounds for Treatment of Cancer and Disorders Associated With Angiogenesis Function UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2011-02-10 US disclosed
WO-2011005520-A1 DEUTERIUM-MODIFIED TRIAZOLO-PYRIDAZINE DERIVATIVES AS GABA-A RECEPTOR MODULATORS CONCERT PHARMACEUTICALS, INC. (US) 2011-01-13 WO disclosed
WO-2011005520-A1 DEUTERIUM-MODIFIED TRIAZOLO-PYRIDAZINE DERIVATIVES AS GABA-A RECEPTOR MODULATORS CONCERT PHARMACEUTICALS, INC. (US) 2011-01-13 WO disclosed
US-20100222318-A1 COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE VERTEX PHARMACEUTICALS INCORPORATED (US) 2010-09-02 US disclosed
WO-2010071837-A1 PYRAZINE DERIVATIVES USEFUL AS INHIBITORS OF ATR KINASE VERTEX PHARMACEUTICALS INCORPORATED (US) 2010-06-24 WO disclosed
US-20100113532-A1 MODULATORS OF THE GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-kB ACTIVITY AND USE THEREOF BRISTOL-MYERS SQUIBB COMPANY 2010-05-06 US disclosed
US-7642273-B2 Bridged tricyclic (e.g 9,10-ethanoanthracene) derivatives of (2-carbonylamino)thiazol-5-yloxoacetamides; treating diseases associated with modulation of the glucocorticoid receptor, AP-1, and/or NF- kappa B activity including obesity, diabetes, inflammatory and immune diseases BRISTOL-MYERS SQUIBB COMPANY (US) 2010-01-05 US disclosed
EP-2124913-A1 1-AMINOMETHYL- L- PHENYL- CYCLOHEXANE DERIVATIVES AS DDP-IV INHIBITORS Novartis AG (CH) 2009-12-02 EP disclosed
CN-101553486-A Oxadiazole and thiadiazole compounds and their use as nicotinic acetylcholine receptor modulators NEUROSEARCH AS (DK) 2009-10-07 CN disclosed
WO-2009109991-A2 NOVEL HYDRAZIDE CONTAINING TYROSINE KINASE INHIBITORS SUN PHARMA ADVANCED RESEARCH COMPANY LTD., (IN) 2009-09-11 WO disclosed
WO-2009111442-A1 AMINO-QUINOXALINE AND AMINO-QUINOLINE COMPOUNDS FOR USE AS ADENOSINE A2a RECEPTOR ANTAGONISTS SCHERING CORPORATION (US) 2009-09-11 WO disclosed
CN-101514176-A Compound N-fluorobenzamido-N'-phenylthiocarbamide as well as preparation and application thereof UNIV NORTHWEST NORMAL (CN) 2009-08-26 CN disclosed
CN-101514176-A Compound N-fluorobenzamido-N'-phenylthiocarbamide as well as preparation and application thereof UNIV NORTHWEST NORMAL (CN) 2009-08-26 CN disclosed
CN-101500993-A 2-aminocarbonylphenylamino-2-phenylacetamides as factor VIIa inhibitors useful as anticoagulants BRISTOL MYERS SQUIBB CO (US) 2009-08-05 CN disclosed
EP-2079734-A1 OXADIAZOLE AND THIADIAZOLE COMPOUNDS AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS NeuroSearch A/S (DK) 2009-07-22 EP disclosed
US-20090124629-A1 3-(1,2,4-TRIAZOL-3YLALKYL) AZABRICLO (3.1.0) HEXANE DERIVATIVES AS MODULATORS OF DOPAMINE D3 RECEPTORS GLAXO GROUP LIMITED (GB) 2009-05-14 US disclosed
US-20090093489-A1 NOVEL COMPOUNDS FOR TREATMENT OF CANCER AND DISORDERS ASSOCIATED WITH ANGIOGENESIS FUNCTION UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2009-04-09 US disclosed
CN-100465168-C Oxdiazole derivative and application thereof in electroluminescent material UNIV EAST CHINA SCIENCE & TECH (CN) 2009-03-04 CN disclosed
WO-2008077597-A1 1-AMINOMETHYL- L- PHENYL- CYCLOHEXANE DERIVATIVES AS DDP-IV INHIBITORS NOVARTIS AG (CH) 2008-07-03 WO disclosed
WO-2008049864-A1 OXADIAZOLE AND THIADIAZOLE COMPOUNDS AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS NEUROSEARCH A/S (DK) 2008-05-02 WO disclosed
US-7358242-B2 Tetraazabenzo[e]azulene derivatives and analogs thereof PFIZER INC. (US) 2008-04-15 US disclosed
EP-1869017-A1 3- (1,2,4-TRIAZOL-3YLALKYL) AZABRICLO (3.1.0) HEXANE DERIVATIVES AS MODULATORS OF DOPAMINE D3 RECEPTORS GLAXO GROUP LIMITED (GB) 2007-12-26 EP disclosed
US-20070265193-A1 TETRAAZABENZO[E]AZULENE DERIVATIVES AND ANALOGS THEREOF PFIZER INC 2007-11-15 US disclosed
US-20070265231-A1 Hydrazide Compounds for Combating Animal Pests BASF AKTIENGESELLSCHAFT (DE) 2007-11-15 US disclosed
US-20070232594-A1 Aromatic amide derivatives, medicinal compositions containing the same, medical uses of both KISSEI PHARMACEUTICAL CO., LTD. (JP) 2007-10-04 US disclosed
EP-1836176-A1 MODULATORS OF THE GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-kB ACTIVITY AND USE THEROF Brystol-Myers Squibb Company (US) 2007-09-26 EP disclosed
US-7265104-B2 Tetraazabenzo[e]azulene derivatives and analogs thereof PFIZER INC. (US) 2007-09-04 US disclosed
EP-1121361-B1 PYRAZOLO-TRIAZINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS MERCK SHARP & DOHME (GB) 2007-08-29 EP disclosed
EP-1819224-A1 HYDRAZIDE COMPOUNDS FOR COMBATING ANIMAL PESTS BASF AKTIENGESELLSCHAFT (DE) 2007-08-22 EP disclosed
US-20070179189-A1 Modulators of the glucocorticoid receptor, AP-1, and/or NF-kB activity and use thereof BRISTOL-MYERS SQUIBB COMPANY 2007-08-02 US disclosed
EP-1813603-A1 AROMATIC AMIDE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME, MEDICAL USES OF BOTH Kissei Pharmaceutical Co., Ltd. (JP) 2007-08-01 EP disclosed
CN-1303115-C Catalysis system of nitrogen-accessory ingredient of oxygen and nickel in use for polymerizaton of norborene and ramification, preparation method and application XIANGYANG CATALYST CO LTD YING (CN) 2007-03-07 CN disclosed
CN-1919842-A Oxdiazole derivative and application thereof in electroluminescent material UNIV EAST CHINA SCIENCE & TECH (CN) 2007-02-28 CN disclosed
EP-1753766-A1 TETRAAZABENZO(E)AZULENE DERIVATIVES AND ANALOGS THEREOF Pfizer Products Inc. (US) 2007-02-21 EP disclosed
EP-1392219-A4 SUBSTITUTED N'-(ARYLCARBONYL)-BENZHYDRAZIDES, N'-(ARYLCARBONYL)-BENZYLIDENE-HYDRAZIDES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOTOSIS AND THE USE THEREOF CYTOVIA INC (US) 2007-01-24 EP disclosed
WO-2006108701-A1 3- (1,2,4-TRIAZOL-3YLALKYL) AZABRICLO (3.1.0) HEXANE DERIVATIVES AS MODULATORS OF DOPAMINE D3 RECEPTORS GLAXO GROUP LIMITED (GB) 2006-10-19 WO disclosed
WO-2006076702-A1 MODULATORS OF THE GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-ĸB ACTIVITY AND USE THEREOF BRISTOL-MYERS SQUIBB COMPANY (US) 2006-07-20 WO disclosed
US-7074813-B2 Substituted N′-(arylcarbonyl)-benzhydrazides, N′-(arylcarbonyl)-benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof CYTOVIA, INC. (US) 2006-07-11 US disclosed
CN-1260239-C Fructose spiro-compound with anti-cancer activity UNIV BEIJING (CN) 2006-06-21 CN disclosed
WO-2006058730-A1 HYDRAZIDE COMPOUNDS FOR COMBATING ANIMAL PESTS BASF AKTIENGESELLSCHAFT (DE) 2006-06-08 WO disclosed
WO-2005116034-A1 TETRAAZABENZO[E]AZULENE DERIVATIVES AND ANALOGS THEREOF PFIZER PRODUCTS INC. (US) 2005-12-08 WO disclosed
US-20050267100-A1 Tetraazabenzo[e]azulene derivatives and analogs thereof PFIZER INC 2005-12-01 US disclosed
EP-1529045-A2 NEW COMPOUNDS Astra Zeneca AB (SE) 2005-05-11 EP disclosed
US-20050075375-A1 Heterocyclic compounds for treating hepatitis C virus ANADYS PHARMACEUTICALS, INC. (US) 2005-04-07 US disclosed
US-6872720-B2 Pyrazolo-triazine derivatives as ligands for gaba receptors MERCK SHARP & DOHME LTD. 2005-03-29 US disclosed
CN-1563113-A Catalysis system of nitrogen-accessory ingredient of oxygen and nickel in use for polymerizaton of norborene and ramification, preparation method and application XIANGYANG CATALYST CO LTD YING (CN) 2005-01-12 CN disclosed
WO-2004110351-A2 HETEROCYCLIC COMPOUNDS FOR TREATING HEPATITIS C VIRUS ANADYS PHARMACEUTICALS, INC. (US) 2004-12-23 WO disclosed
US-6828322-B2 Substituted 1,2, 4-triazolo(4,3-b)pyridazine derivatives; anxiolytic; anticonvulsant; antimigraine MERCK SHARP & DOHME LTD. 2004-12-07 US disclosed
US-20040186078-A1 Substituted N'-(arylcarbonyl)-benzhydrazides, N'-(arylcarbonyl)-benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof CYTOVIA, INC. 2004-09-23 US disclosed
CN-1530371-A Fructose spiro-compound with anti-cancer activity 北京大学 2004-09-22 CN disclosed
EP-1430898-A1 RECEPTOR ANTAGONIST KYOWA HAKKO KOGYO CO., LTD. (JP) 2004-06-23 EP disclosed
US-20040110826-A1 Receptor Antagonists KYOWA HAKKO KOGYO CO., LTD. (JP) 2004-06-10 US disclosed
CN-1148357-C Triazole and imidazole derivative - 2004-05-05 CN disclosed
US-6716859-B2 ANTICANCER AGENTS CYTOVIA, INC. 2004-04-06 US disclosed
US-20040063714-A1 Triazolo-pyridazine derivatives as ligands for GABA receptors CARLING WILLIAM ROBERT (GB) 2004-04-01 US disclosed
EP-1392219-A2 SUBSTITUTED N'-(ARYLCARBONYL)-BENZHYDRAZIDES, N'-(ARYLCARBONYL)-BENZYLIDENE-HYDRAZIDES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOTOSIS AND THE USE THEREOF Cytovia, Inc. (US) 2004-03-03 EP disclosed
WO-2004014881-A2 '1,2,4'OXADIAZOLES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTOR-5 ASTRA ZENECA AB (SE) 2004-02-19 WO disclosed
US-6630471-B1 Central nervous system disorders MERCK SHARP & DOHME LTD. (GB) 2003-10-07 US disclosed
US-6579875-B1 Treatment of anxiety and convulsions; 7-cyclobutyl-3-(2,6-difluorophenyl)-6-(2-methyl-2H-1,2,4-triazol-3 -ylmethyoxy)-1,2,4-triazolo(4,3-b) pyridazine MERCK SHARP & DOHME LIMITED 2003-06-17 US disclosed
EP-1090004-B1 A SUBSTITUTED TRIAZOLO-PYRIDAZINE DERIVATIVE, PHARMACEUTICAL COMPOSITIONS MADE THEREFROM MERCK SHARP & DOHME (GB) 2003-05-07 EP disclosed
EP-0915875-B1 SUBSTITUTED TRIAZOLO-PYRIDAZINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS MERCK SHARP & DOHME (GB) 2003-04-09 EP disclosed
US-20030060467-A1 Pyrazolo-triazine derivatives as ligands for gaba receptors MERCK SHARP & DOHME LTD. (GB) 2003-03-27 US disclosed
EP-1282623-A1 PYRAZOLO-TRIAZINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS MERCK SHARP & DOHME LTD. (GB) 2003-02-12 EP disclosed
US-20030013743-A1 Substituted N'-(arylcarbonyl)-benzhydrazides, N'-(arylcarbonyl)-benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof CYTOVIA, INC. 2003-01-16 US disclosed
WO-2002089745-A2 SUBSTITUTED N'-(ARYLCARBONYL)-BENZHYDRAZIDES, N'-(ARYLCARBONYL)-BENZYLIDENE-HYDRAZIDES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF CYTOVIA, INC. (US) 2002-11-14 WO disclosed
CN-1379777-A Amino-triazolopyridine derivatives HOFFMANN LA ROCHE (CH) 2002-11-13 CN disclosed
US-6476030-B1 Pyrazolo-triazine derivatives as ligands for GABA receptors MERCK SHARP & DOHME LTD. 2002-11-05 US disclosed
EP-1214322-A2 AMINO-TRIAZOLOPYRIDINE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2002-06-19 EP disclosed
US-6355653-B1 DRUG AND CARRIER FOR ANTIALLERGENS, BRAIN DISORDERS AND NEUROTRANSMITTERS HOFFMANN-LA ROCHE INC. 2002-03-12 US disclosed
EP-1150983-A1 TRIAZOLO-PYRIDAZINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS MERCK SHARP & DOHME LTD. (GB) 2001-11-07 EP disclosed
WO-2001077111-A1 PYRAZOLO-TRIAZINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS MERCK SHARP & DOHME LIMITED (GB) 2001-10-18 WO disclosed
US-6303597-B1 FOR THERAPY OF ANXIETY AND CONVULSIONS MERCK SHARP & DOHME LIMITED (GB) 2001-10-16 US disclosed
EP-1121361-A1 PYRAZOLO-TRIAZINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS Merck Sharp & Dohme Limited (GB) 2001-08-08 EP disclosed
US-6255305-B1 PSYCHOLOGICAL DISORDERS MERCK SHARP & DOHME LIMITED (GB) 2001-07-03 US disclosed
CN-1066722-C Novel acaricidally active tetrazine derivatives CHINOIN GYOGYSZER ES VEGYESZET (HU) 2001-06-06 CN disclosed
EP-1090004-A1 A SUBSTITUTED TRIAZOLO-PYRIDAZINE DERIVATIVE, PHARMACEUTICAL COMPOSITIONS MADE THEREFROM Merck Sharp & Dohme Limited (GB) 2001-04-11 EP disclosed
WO-2001017999-A2 AMINO-TRIAZOLOPYRIDINE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2001-03-15 WO disclosed
CN-1281852-A Triazole and imidazole derivative HOFFMANN LA ROCHE (CH) 2001-01-31 CN disclosed
EP-1049696-A1 TRIAZOLO-PYRIDAZINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS MERCK SHARP & DOHME LTD. (GB) 2000-11-08 EP disclosed
EP-1047697-A1 TRIAZOLO-PYRIDAZINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS MERCK SHARP & DOHME LTD. (GB) 2000-11-02 EP disclosed
WO-2000047582-A1 TRIAZOLO-PYRIDAZINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS MERCK SHARP & DOHME LIMITED (GB) 2000-08-17 WO disclosed
WO-2000023449-A1 PYRAZOLO-TRIAZINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS MERCK SHARP & DOHME LIMITED (GB) 2000-04-27 WO disclosed
WO-1999067245-A1 A SUBSTITUTED TRIAZOLO-PYRIDAZINE DERIVATIVE, PHARMACEUTICAL COMPOSITIONS MADE THEREFROM MERCK SHARP & DOHME LIMITED (GB) 1999-12-29 WO disclosed
WO-1999067245-A1 A SUBSTITUTED TRIAZOLO-PYRIDAZINE DERIVATIVE, PHARMACEUTICAL COMPOSITIONS MADE THEREFROM MERCK SHARP & DOHME LIMITED (GB) 1999-12-29 WO disclosed
WO-1999037644-A1 TRIAZOLO-PYRIDAZINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS MERCK SHARP & DOHME LIMITED (GB) 1999-07-29 WO disclosed
WO-1999036423-A1 TRIAZOLO-PYRIDAZINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS MERCK SHARP & DOHME LIMITED (GB) 1999-07-22 WO disclosed
EP-0915875-A2 SUBSTITUTED TRIAZOLO-PYRIDAZINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS MERCK SHARP & DOHME LTD. (GB) 1999-05-19 EP disclosed
WO-1998004559-A2 SUBSTITUTED TRIAZOLO-PYRIDAZINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS MERCK SHARP & DOHME LIMITED (GB) 1998-02-05 WO disclosed
EP-0725776-B1 3-ARYL-4-ALKYL AND 4,5-DIALKYL-4H-1,2,4-TRIAZOLES USEFUL AS MEMORY ENHANCERS MERRELL PHARMA INC (US) 1997-07-16 EP disclosed
EP-0725776-A1 3-ARYL-4-ALKYL AND 4,5-DIALKYL-4H-1,2,4-TRIAZOLES USEFUL AS MEMORY ENHANCERS MERRELL PHARMA INC (US) 1996-08-14 EP disclosed
WO-1995011887-A1 3-ARYL-4-ALKYL AND 4,5-DIALKYL-4H-1,2,4-TRIAZOLES USEFUL AS MEMORY ENHANCERS MERRELL PHARMACEUTICALS INC. (US) 1995-05-04 WO disclosed
US-5334726-A Controlling weeds ROHM AND HAAS COMPANY (US) 1994-08-02 US disclosed
EP-0296479-B1 Fluorobenzoates and process for their production IHARA CHEMICAL IND CO (JP) 1994-03-30 EP disclosed
EP-0263071-B1 2-Substituted-e-fused-[1,2,4]-triazolo[1,5-c] pyrimidines, pharmaceutical compositions, and uses thereof CIBA-GEIGY AG (CH) 1992-08-12 EP disclosed
US-5134236-A Analgesics, antidepressants, anticonvulsants HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1992-07-28 US disclosed
US-5120347-A Pre and postemergence ROHM AND HAAS COMPANY (US) 1992-06-09 US disclosed
US-4999356-A Analgesics, antidepressants, anticonvulsants HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) 1991-03-12 US disclosed
EP-0217748-B1 2-Substituted-e-fused-[1,2,4,]triazolo-[1,5-c]pyrimidines pharmaceutical compositions and uses thereof CIBA-GEIGY AG (CH) 1991-02-06 EP disclosed
EP-0185256-B1 TRIAZOLE DERIVATES, THEIR PREPARATION AND THEIR USE AS PESTICIDES CIBA-GEIGY AG (CH) 1991-01-30 EP disclosed
US-4916253-A Fluorobenzoates and process for their production IHARA CHEMICAL INDUSTRY COMPANY, LTD. (JP) 1990-04-10 US disclosed
CN-1039016-A N '-replacement-N, N '-two replaces the hydrazine insect repellent ROHM & HAAS (US) 1990-01-24 CN disclosed
US-4831013-A BENZODIAZEPINE RECEPTOR ANTAGONISTS CIBA-GEIGY CORPORATION (US) 1989-05-16 US disclosed
EP-0302423-A2 1-Phenyl-3-(1-piperazinyl)-1h-indazoles, a process and intermediates for their preparation, and the use thereof as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1989-02-08 EP disclosed
EP-0296479-A2 Fluorobenzoates and process for their production IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) 1988-12-28 EP disclosed
US-4788210-A PESTICIDES HOFFMANN-LA ROCHE INC. (US) 1988-11-29 US disclosed
WO-1988002370-A1 2-SUBSTITUTED-E-FUSED-[1,2,4]TRIAZOLO[1,5-C]PYRIMIDINES PHARMACEUTICAL COMPOSITIONS AND USES THEREOF CIBA-GEIGY AG (CH) 1988-04-07 WO disclosed
EP-0263071-A1 2-Substituted-e-fused-[1,2,4]-triazolo[1,5-c] pyrimidines, pharmaceutical compositions, and uses thereof CIBA-GEIGY AG (CH) 1988-04-06 EP disclosed
US-4713383-A ADENOSINE AND BENZODIAZEPINE ANTAGONISTS CIBA-GEIGY CORPORATION (US) 1987-12-15 US disclosed
EP-0217748-A2 2-Substituted-e-fused-[1,2,4,]triazolo-[1,5-c]pyrimidines pharmaceutical compositions and uses thereof CIBA-GEIGY AG (CH) 1987-04-08 EP disclosed
EP-0185256-A2 Triazole derivates, their preparation and their use as pesticides CIBA-GEIGY AG (CH) 1986-06-25 EP disclosed
EP-0181282-A1 Triazoloquinazoline compounds CIBA-GEIGY AG (CH) 1986-05-14 EP disclosed
US-4166129-A AGRICULTURAL AND HORTICULTURAL N-BENZOYL-N'-TRICHLOROETHYLIDENE HYDRAZINE FUNGICIDES KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1979-08-28 US disclosed
US-4166129-A AGRICULTURAL AND HORTICULTURAL N-BENZOYL-N'-TRICHLOROETHYLIDENE HYDRAZINE FUNGICIDES KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1979-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (50 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220235062-A1 P2X7 MODULATORS P2RX7, P2RX4, P2RX1 GAA 3113/4885MEN1 3119/4885KMT2A 4518/4885
US-20240300932-A1 N-PHENYLIMINE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF PNMT, NNMT, PAH GAA 2756/4885MEN1 1534/4885KMT2A 1378/4885
US-20200308189-A1 FUSED TRIAZOLE AGONISTS OF THE APJ RECEPTOR TBXA2R, AP3M1, GPBAR1 GAA 4300/4885MEN1 4086/4885KMT2A 4306/4885
US-20190284173-A1 TRIAZOLE PHENYL COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR AGTR1, AGTR2, TBXA2R GAA 4237/4885MEN1 4636/4885KMT2A 3930/4885
US-20090124629-A1 3-(1,2,4-TRIAZOL-3YLALKYL) AZABRICLO (3.1.0) HEXANE DERIVATIVES AS MODULATORS OF DOPAMINE D3 RECEPTORS DRD3, HTR3C, TACR2 GAA 4880/4885MEN1 3837/4885KMT2A 4062/4885
US-10961232-B2 Substituted pyrazines as ATR kinase inhibitors ATR, MAP3K5, CHEK1 GAA 2559/4885MEN1 2596/4885KMT2A 1482/4885
US-12539339-B2 Radiopharmaceutical conjugate compound for diagnosis and/or therapeutic uses thereof SLC7A1, SLC39A11, SLC39A3 GAA 282/4885MEN1 774/4885KMT2A 162/4885
US-12338243-B2 P2X7 modulators P2RX7, P2RX4, P2RX1 GAA 3113/4885MEN1 3119/4885KMT2A 4518/4885
US-20100222318-A1 COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE ATR, CHEK1, MAP3K5 GAA 1759/4885MEN1 2273/4885KMT2A 1708/4885
US-20040063714-A1 Triazolo-pyridazine derivatives as ligands for GABA receptors GABRA3, GABBR1, GABRA2 GAA 4157/4885MEN1 4476/4885KMT2A 1496/4885
US-12331044-B2 Inhibitors of histone deacetylase useful for the treatment or prevention of HIV infection HDAC1, HDAC11, HDAC10 GAA 410/4885MEN1 3585/4885KMT2A 88/4885
US-11634391-B2 Compounds which are inhibitors of Notum NOTUM, GOT2, GOT1 GAA 27/4885MEN1 2634/4885KMT2A 4180/4885
US-20130317033-A1 SUBSTITUTED TRIAZOLO-PYRIDAZINE DERIVATIVES GABRA5, GABRA2, GABRA3 GAA 2767/4885MEN1 3254/4885KMT2A 1758/4885
US-20070265193-A1 TETRAAZABENZO[E]AZULENE DERIVATIVES AND ANALOGS THEREOF CCKAR, CCKBR, GLP1R GAA 975/4885MEN1 1596/4885KMT2A 3726/4885
US-10118930-B2 Piperidinylpyrazolopyrimidinones and their use HAMP, SERPINC1, PRSS8 GAA 4335/4885MEN1 1501/4885KMT2A 3881/4885
US-20170174619-A1 HDAC INHIBITOR COMPOUNDS AND METHODS OF TREATMENT HDAC4, HDAC1, HDAC5 GAA 436/4885MEN1 2835/4885KMT2A 62/4885
US-20040186078-A1 Substituted N'-(arylcarbonyl)-benzhydrazides, N'-(arylcarbonyl)-benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof CASP2, CASP1, BCL2 GAA 2351/4885MEN1 2707/4885KMT2A 2862/4885
US-20210171534-A1 Pyrrolopyrimidines as CFTR Potentiators CFTR, P2RX1, P2RX5 GAA 3288/4885MEN1 4087/4885KMT2A 4318/4885
US-20100113532-A1 MODULATORS OF THE GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-kB ACTIVITY AND USE THEREOF NFRKB, NFKBIA, NFKB2 GAA 3237/4885MEN1 4568/4885KMT2A 3508/4885
US-20210276992-A1 INHIBITORS OF HISTONE DEACETYLASE USEFUL FOR THE TREATMENT OR PREVENTION OF HIV INFECTION HDAC1, HDAC11, HDAC10 GAA 410/4885MEN1 3585/4885KMT2A 88/4885
US-20150031661-A1 COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE ATR, CHEK1, MAP3K5 GAA 1759/4885MEN1 2273/4885KMT2A 1708/4885
US-20180118749-A1 P2X7 MODULATORS P2RX7, P2RX3, P2RX1 GAA 2522/4885MEN1 3055/4885KMT2A 4030/4885
US-10906890-B2 Triazole phenyl compounds as agonists of the APJ receptor AGTR1, AGTR2, TBXA2R GAA 4237/4885MEN1 4636/4885KMT2A 3930/4885
US-20170334917-A1 PIPERIDINYLPYRAZOLOPYRIMIDINONES AND THEIR USE HAMP, SERPINC1, PRSS8 GAA 4335/4885MEN1 1501/4885KMT2A 3881/4885
US-11731934-B2 HDAC inhibitor compounds and methods of treatment HDAC4, HDAC1, HDAC5 GAA 436/4885MEN1 2835/4885KMT2A 62/4885
US-20200017512-A1 PYRROLOPYRIMIDINES AS CFTR POTENTIATORS CFTR, P2RX1, P2RX5 GAA 3288/4885MEN1 4087/4885KMT2A 4318/4885
US-20050075375-A1 Heterocyclic compounds for treating hepatitis C virus HAVCR2, HCCS, LIPC GAA 519/4885MEN1 3473/4885KMT2A 3600/4885
US-20190047995-A1 COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE ATR, CHEK1, MAP3K5 GAA 1759/4885MEN1 2273/4885KMT2A 1708/4885
US-20210171475-A1 COMPOUNDS GOT2, GOT1, OAT GAA 36/4885MEN1 2737/4885KMT2A 3672/4885
US-20190225621-A1 PYRROLOPYRIMIDINES AS CFTR POTENTIATORS CFTR, P2RX1, P2RX5 GAA 3288/4885MEN1 4087/4885KMT2A 4318/4885
US-20230030414-A1 COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE ATR, CHEK1, MAP3K5 GAA 1759/4885MEN1 2273/4885KMT2A 1708/4885
US-20230250100-A1 Pyrrolopyrimidines as CFTR Potentiators CFTR, P2RX1, P2RX5 GAA 3288/4885MEN1 4087/4885KMT2A 4318/4885
US-20110034472-A1 Novel Compounds for Treatment of Cancer and Disorders Associated With Angiogenesis Function VEGFA, TEK, MCL1 GAA 2881/4885MEN1 2560/4885KMT2A 3993/4885
US-20110105513-A1 AMINO-QUINOXALINE AND AMINO-QUINOLINE COMPOUNDS FOR USE AS ADENOSINE A2a RECEPTOR ANTAGONISTS ADORA2A, ADORA1, ADORA3 GAA 2262/4885MEN1 3052/4885KMT2A 3025/4885
US-10040741-B2 Method for manufacturing high purity glycol based compound GK, GMDS, UGCG GAA 146/4885MEN1 4140/4885KMT2A 1667/4885
US-20110065711-A1 SUBSTITUTED TRIAZOLO-PYRIDAZINE DERIVATIVES GABRA5, GABRA2, GABRA3 GAA 2767/4885MEN1 3254/4885KMT2A 1758/4885
US-20090093489-A1 NOVEL COMPOUNDS FOR TREATMENT OF CANCER AND DISORDERS ASSOCIATED WITH ANGIOGENESIS FUNCTION VEGFA, TEK, MCL1 GAA 2881/4885MEN1 2560/4885KMT2A 3993/4885
US-20040110826-A1 Receptor Antagonists ADRA2C, OPRL1, ADRB1 GAA 1429/4885MEN1 4885/4885KMT2A 3079/4885
US-20210009509-A1 HDAC INHIBITOR COMPOUNDS AND METHODS OF TREATMENT HDAC4, HDAC1, HDAC5 GAA 436/4885MEN1 2835/4885KMT2A 62/4885
US-12612409-B2 Pyrrolopyrimidines as CFTR potentiators CFTR, CLCN2, SLC26A3 GAA 2850/4885MEN1 4738/4885KMT2A 4855/4885
US-20050267100-A1 Tetraazabenzo[e]azulene derivatives and analogs thereof CCKAR, CCKBR, GPR119 GAA 672/4885MEN1 2268/4885KMT2A 3050/4885
US-20160297732-A1 METHOD FOR MANUFACTURING HIGH PURITY GLYCOL BASED COMPOUND GK, GMDS, UGCG GAA 146/4885MEN1 4140/4885KMT2A 1667/4885
US-20030060467-A1 Pyrazolo-triazine derivatives as ligands for gaba receptors GABRA5, GABRA3, GABRA4 GAA 4466/4885MEN1 4649/4885KMT2A 1302/4885
US-20030013743-A1 Substituted N'-(arylcarbonyl)-benzhydrazides, N'-(arylcarbonyl)-benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof CASP2, CASP1, BCL2 GAA 2351/4885MEN1 2707/4885KMT2A 2862/4885
US-11149040-B2 Fused triazole agonists of the APJ receptor TBXA2R, AP3M1, GPBAR1 GAA 4300/4885MEN1 4086/4885KMT2A 4306/4885
US-10301315-B2 Pyrrolopyrimidines as CFTR potentiators CFTR, P2RX1, P2RX5 GAA 3468/4885MEN1 4154/4885KMT2A 4332/4885
US-20070265231-A1 Hydrazide Compounds for Combating Animal Pests HRH4, CBR3, HRH2 GAA 3419/4885MEN1 2754/4885KMT2A 3080/4885
US-20180141954-A1 PYRROLOPYRIMIDINES AS CFTR POTENTIATORS CFTR, P2RX1, P2RX5 GAA 3468/4885MEN1 4154/4885KMT2A 4332/4885
US-20070232594-A1 Aromatic amide derivatives, medicinal compositions containing the same, medical uses of both AVPR2, AVPR1A, AVPR1B GAA 2544/4885MEN1 1330/4885KMT2A 3221/4885
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“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.