Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.49 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | VCP | P55072 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7205479 | 0.90 | VCP (0.44) | HSP90AA1NTSR1HPGDSRAB9AVCP | |
| SCHEMBL7200606 | 0.86 | APP (0.49) | HSP90AA1NTSR1RAB9AVCPFFAR1 | |
| SCHEMBL7204230 | 0.85 | APP (0.47) | RAB9AVCPFFAR1MAPTALDH1A1 | |
| SCHEMBL7203523 | 0.85 | RAB9A (0.49) | RAB9AVCPFFAR1MAPTALDH1A1 | |
| SCHEMBL7204585 | 0.85 | APP (0.51) | HSP90AA1NTSR1RAB9AVCPFFAR1 | |
| SCHEMBL7203532 | 0.85 | MAPT (0.44) | HSP90AA1NTSR1VCPFFAR1MAPT | |
| SCHEMBL7201310 | 0.85 | VCP (0.57) | RAB9AVCPFFAR1MAPTALDH1A1 | |
| SCHEMBL7200317 | 0.82 | CES2 (0.44) | RAB9AFFAR1GRM5CES1 | |
| SCHEMBL7203118 | 0.81 | KCNK3 (0.45) | RAB9AMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL7200878 | 0.81 | APP (0.54) | RAB9AMAPTALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0476645-B1 | Calcium uptake inhibitors | MERRELL DOW PHARMA (US) | 1995-09-06 | — | — | EP | claimed |
| EP-0476645-A1 | Calcium uptake inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-03-25 | — | — | EP | claimed |
| US-6605730-B2 | 3-(2-Thienyl)-5-phenyl-1H-pyrazole compounds of given formula | NIHON BAYER AGROCHEM K.K. (JP) | 2003-08-12 | — | — | US | disclosed |
| US-20030028034-A1 | Nematicidal pyrazoles | WADA KATSUAKI (JP) | 2003-02-06 | — | — | US | disclosed |
| US-6310049-B1 | 3-(2-THIENYL),5-(SUBSTITUTED PHENYL)-1H-PYRAZOLES AND 3-(SUBSTITUTED PHENYL),5-(2-THIENYL)-1H-PYRAZOLES OF GIVEN FORMULA; ANTHELMINTICS | NIHON BAYER AGROCHEM K.K. (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-1104418-A2 | NEMATICIDAL PYRAZOLES | NIHON BAYER AGROCHEM K.K. (JP) | 2001-06-06 | — | — | EP | disclosed |
| WO-2000009500-A2 | NEMATICIDAL PYRAZOLES | NIHON BAYER AGROCHEM K.K. (JP) | 2000-02-24 | — | — | WO | disclosed |
| EP-0476645-B1 | Calcium uptake inhibitors | MERRELL DOW PHARMA (US) | 1995-09-06 | — | — | EP | disclosed |
| US-5409942-A | Administering 1-phenyl-3-aryl-2-propyne-1-ones compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1995-04-25 | — | — | US | disclosed |
| US-5223518-A | Controlling intake in leukocytes and platelets | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-06-29 | — | — | US | disclosed |
| EP-0476645-A1 | Calcium uptake inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-03-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030028034-A1 | Nematicidal pyrazoles | CBR3, CBR1, CCR4 | HSP90AA1 631/4885NTSR1 1507/4885HPGDS 2920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.