Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.59 |
| ▸ | MDM4 | O15151 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CETP | P11597 | 3/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30761772 | 0.86 | ALDH1A1 (0.56) | ALDH1A1HTTTSHR | |
| SCHEMBL7089269 | 0.86 | ALDH1A1 (0.56) | ALDH1A1HTTTSHR | |
| SCHEMBL5814278 | 0.78 | NPC1 (0.64) | ALDH1A1HTT | |
| SCHEMBL30782571 | 0.78 | GAA (0.53) | TP53ALDH1A1HTTTSHR | |
| SCHEMBL4048833 | 0.78 | GAA (0.53) | TP53ALDH1A1HTTTSHR | |
| SCHEMBL9816795 | 0.78 | MAPT (0.53) | — | |
| SCHEMBL1534004 | 0.78 | MDM4 (0.66) | TP53MDM4ALDH1A1CETPMDM2 | |
| SCHEMBL3837851 | 0.78 | MAPT (0.52) | TP53ALDH1A1HTTTSHR | |
| SCHEMBL23169175 | 0.77 | HTT (0.64) | ALDH1A1HTT | |
| SCHEMBL8927627 | 0.77 | ALDH1A1 (0.49) | ALDH1A1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903350-B1 | Pyrrolotriazole derivative | FUJI PHOTO FILM CO LTD (JP) | 2003-03-12 | — | — | EP | disclosed |
| EP-0518238-B1 | Pyrrolotriazole derivative | FUJI PHOTO FILM CO LTD (JP) | 1999-04-07 | — | — | EP | disclosed |
| EP-0903350-A1 | Pyrrolotriazole derivative | FUJI PHOTO FILM CO., LTD. (JP) | 1999-03-24 | — | — | EP | disclosed |
| US-5508421-A | Pyrrolotriazole azomethine dye, and heat transfer dye providing material containing a pyrrolotriazole azomethine dye | FUJI PHOTO FILM CO., LTD. (JP) | 1996-04-16 | — | — | US | disclosed |
| US-5362882-A | Intermediates for dyes for polyesters, images for heat sensitive elements and electrography | FUJI PHOTO FILM CO., LTD. (JP) | 1994-11-08 | — | — | US | disclosed |
| EP-0518238-A1 | Pyrrolotriazole derivative | FUJI PHOTO FILM CO., LTD. (JP) | 1992-12-16 | — | — | EP | disclosed |