Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30782571 | 1.00 | GAA (0.53) | GAAHTTNPC1LMNATP53 | |
| SCHEMBL7089269 | 0.87 | ALDH1A1 (0.56) | HTTKDM4EALDH1A1TSHR | |
| SCHEMBL30761772 | 0.87 | ALDH1A1 (0.56) | HTTKDM4EALDH1A1TSHR | |
| SCHEMBL7250890 | 0.82 | HTT (0.49) | HTTTP53MAPTALDH1A1TSHR | |
| SCHEMBL5814278 | 0.80 | NPC1 (0.64) | HTTNPC1LMNAKMT2AKDM4E | |
| SCHEMBL7256367 | 0.79 | ABCC1 (0.55) | GAAHTTNPC1LMNATP53 | |
| SCHEMBL3837851 | 0.79 | MAPT (0.52) | HTTTP53MAPTALDH1A1TSHR | |
| SCHEMBL11133449 | 0.79 | MAPT (0.54) | GAAHTTNPC1LMNATP53 | |
| SCHEMBL23169175 | 0.78 | HTT (0.64) | HTTNPC1LMNAKMT2AALDH1A1 | |
| SCHEMBL7202775 | 0.78 | TP53 (0.59) | HTTTP53ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3147323-B2 | THERMALLY EXPANDABLE COMPOSITIONS WITH POLYSACCHARIDE | HENKEL AG & CO KGAA (DE) | 2022-12-28 | — | — | EP | claimed |
| US-11505669-B2 | Thermally expandable compositions comprising urea derivatives | HENKEL AG & CO. KGAA (DE) | 2022-11-22 | — | — | US | claimed |
| US-11441004-B2 | Thermally expandable compositions comprising polysaccharide | HENKEL AG & CO. KGAA (DE) | 2022-09-13 | — | — | US | claimed |
| CN-108137883-B | Thermally expandable composition comprising a polysaccharide | 汉高股份有限及两合公司 | 2021-12-14 | — | — | CN | claimed |
| CN-108026309-B | Thermally expandable composition comprising urea derivatives | 汉高股份有限及两合公司 | 2021-10-15 | — | — | CN | claimed |
| EP-3356453-B1 | THERMALLY EXPANDABLE COMPOSITIONS CONTAINING UREA DERIVATIVES | HENKEL AG & CO KGAA (DE) | 2020-06-24 | — | — | EP | claimed |
| EP-3147323-B1 | THERMALLY EXPANDABLE COMPOSITIONS WITH POLYSACCHARIDE | HENKEL AG & CO KGAA (DE) | 2020-04-15 | — | — | EP | claimed |
| EP-3356453-A1 | THERMALLY EXPANDABLE COMPOSITIONS COMPRISING UREA DERIVATIVES | Henkel AG & Co. KGaA (DE) | 2018-08-08 | — | — | EP | claimed |
| US-20180215887-A1 | THERMALLY EXPANDABLE COMPOSITIONS COMPRISING POLYSACCHARIDE | HENKEL AG & CO. KGAA (DE) | 2018-08-02 | — | — | US | claimed |
| US-20180215888-A1 | THERMALLY EXPANDABLE COMPOSITIONS COMPRISING UREA DERIVATIVES | HENKEL AG & CO. KGAA (DE) | 2018-08-02 | — | — | US | claimed |
| EP-3147323-A1 | THERMALLY EXPANDABLE COMPOSITIONS WITH POLYSACCHARIDE | Henkel AG & Co. KGaA (DE) | 2017-03-29 | — | — | EP | claimed |
| US-6635091-B2 | Oxidation color dye and coupler | L'OREAL S. A. (FR) | 2003-10-21 | — | — | US | claimed |
| US-20020178512-A1 | Oxidation dyeing composition for keratinous fibres comprising a n-(2-hydrobenzene)-carbamate or a n-(2-hydroxy-benzene)-urea and a pyrazolopyrimine, dyeing methods | L'OREAL SA (FR) | 2002-12-05 | — | — | US | claimed |
| US-20010034914-A1 | Compositions for the oxidation dyeing of keratinous fibers comprising at least one coupler, and dyeing methods | L'OREAL S.A. (FR) | 2001-11-01 | — | — | US | claimed |
| EP-1129689-A2 | Keratinous fiber dyeing composition comprising N-(2-hydroxybenzene)-carbamate or N-(2-hydroxybenzene)urea derivatives as coupling agents and process for dyeing | L'OREAL (FR) | 2001-09-05 | — | — | EP | claimed |
| EP-0108712-B1 | HEAT-CURABLE EPOXY RESIN MIXTURES | CIBA-GEIGY AG (CH) | 1986-03-05 | — | — | EP | claimed |
| US-4404356-A | USING A 2-HYDROXYPHENYL UREA AS CORING AGENT; STORAGE STABILITY; CASTINGS; MOLDING MATERIALS | CIBA-GEIGY CORPORATION (US) | 1983-09-13 | — | — | US | claimed |
| JP-58024574-A | — | — | None | — | — | JP | disclosed |
| JP-S5824574-A | UREA DERIVATIVE AND HERBICIDE CONTAINING IT | HODOGAYA CHEM CO LTD | 1983-02-14 | — | — | JP | disclosed |
| US-3979411-A | FUNGICIDES, INSECTICIDE, MITICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010034914-A1 | Compositions for the oxidation dyeing of keratinous fibers comprising at least one coupler, and dyeing methods | KRT18, FH, FGB | GAA 4640/4885HTT 1274/4885NPC1 4448/4885 |
| US-20020178512-A1 | Oxidation dyeing composition for keratinous fibres comprising a n-(2-hydrobenzene)-carbamate or a n-(2-hydroxy-benzene)-urea and a pyrazolopyrimine, dyeing methods | FH, KRT18, CYB5R3 | GAA 4734/4885HTT 663/4885NPC1 4742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.