Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.37 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL532594 | 0.86 | POLB (0.41) | ADORA2AADORA2BADORA1 | |
| SCHEMBL532593 | 0.85 | TYMP (0.46) | ADORA2AADORA2BADORA1 | |
| Hydroquinone SCHEMBL7070523 | 0.84 | PRMT6 (0.41) | ADORA2AADORA2BADORA3ADORA1PRKAG1 | |
| SCHEMBL4434106 | 0.84 | ADORA2A (0.39) | ADORA2AADORA2BADORA3ADORA1PRKAG1 | |
| SCHEMBL888001 | 0.83 | ADORA3 (0.45) | ADORA2AADORA2BADORA3ADORA1PRKAG1 | |
| SCHEMBL7075967 | 0.82 | ADORA2B (0.39) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL7873202 | 0.82 | ADORA2A (0.42) | ADORA2AADORA2BADORA3ADORA1PRKAG1 | |
| SCHEMBL7879389 | 0.80 | CHKA (0.36) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL2112347 | 0.78 | ADORA3 (0.47) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL21577261 | 0.77 | TYMP (0.46) | ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6569837-B1 | Administering 2'-deoxy-beta-L-erythro-pentofuranonucleoside alone or with another anti-hepatitis B agent such as 3TC (beta-L-2-hydroxymethyl-5-(cytosin-1-yl)-1,3-oxathiolane); use of beta-l-thymidine (telbivudine) | IDENIX PHARMACEUTICALS INC. | 2003-05-27 | — | — | US | disclosed |