Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7199784 | 0.81 | MGAM (0.44) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL8096308 | 0.79 | DGAT1 (0.46) | TSHRDGAT1MGAMGAASI | |
| SCHEMBL12670586 | 0.78 | GAA (0.52) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL12561094 | 0.72 | PRKCA (0.43) | MAPK1HIF1AGAAALDH1A1TP53 | |
| SCHEMBL9443410 | 0.72 | MAPK1 (0.37) | TSHRMAPK1HIF1AMGAMGAA | |
| SCHEMBL12938589 | 0.70 | MAPK1 (0.32) | MAPK1HIF1A | |
| SCHEMBL1597489 | 0.68 | MAPK1 (0.39) | MAPK1HIF1AGAAALDH1A1TP53 | |
| SCHEMBL14075105 | 0.68 | MAPK1 (0.34) | MAPK1HIF1AALDH1A1TP53CYP3A4 | |
| SCHEMBL14075104 | 0.68 | MAPK1 (0.34) | MAPK1HIF1AALDH1A1TP53CYP3A4 | |
| SCHEMBL1171107 | 0.68 | MAPK1 (0.34) | MAPK1HIF1AALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003064502-A1 | POLYESTER DENDRIMERS, METHOD FOR THE MANUFACTURE THEREOF, AND THEIR USE | UNIVERSITY OF JYVÄSKYLÄ (FI) | 2003-08-07 | — | — | WO | disclosed |