SCHEMBL12670586

SCHEMBL12670586

CCOC(=O)C(C(=O)OC)(C(=O)OC)C(=O)OC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.52
MGAM O43451 1/20 0.52
SI P14410 1/20 0.52
MGAM2 Q2M2H8 1/20 0.52
PKM P14618 3/20 0.45
KDM4E B2RXH2 1/20 0.45
THRB P10828 1/20 0.44
ALDH1A1 P00352 4/20 0.43
HTT P42858 1/20 0.42
LMNA P02545 1/20 0.42
HSD17B10 Q99714 1/20 0.42
MMP8 P22894 1/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
ALOX15 P16050 1/20 0.40
SOAT1 P35610 1/20 0.40
CYP4F2 P78329 2/20 0.39
CYP4A11 Q02928 2/20 0.39
MAPT P10636 1/20 0.39
ATM Q13315 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5482996 0.89 MGAM (0.55) GAAMGAMSIMGAM2PKM
SCHEMBL8096308 0.81 DGAT1 (0.46) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL5015136 0.78 DGAT1 (0.54) GAAMGAMSIMGAM2PKM
SCHEMBL29008744 0.78 MEN1 (0.48) GAAMGAMSIMGAM2PKM
SCHEMBL7203544 0.78 TSHR (0.36) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL7199784 0.78 MGAM (0.44) GAAMGAMSIMGAM2PKM
SCHEMBL18453655 0.77 ALDH1A1 (0.46) GAAMGAMSIMGAM2PKM
SCHEMBL28353681 0.77 ALDH1A1 (0.50) GAAMGAMSIMGAM2PKM
SCHEMBL10949469 0.76 PKM (0.43) GAAMGAMSIMGAM2PKM
Hydrochloric Acid SCHEMBL5453463 0.76 DGAT1 (0.52) GAAMGAMSIMGAM2PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150227043-A1 BOTTOM ANTIREFLECTIVE MATERIALS AND COMPOSITIONS AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. 2015-08-13 US disclosed
US-20140295349-A1 BOTTOM ANTIREFLECTIVE MATERIALS AND COMPOSITIONS AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (US) 2014-10-02 US disclosed
US-8551686-B2 Antireflective composition for photoresists AZ ELECTRONIC MATERIALS USA CORP. (US) 2013-10-08 US disclosed
CN-101845013-B Multi-hindered piperidyl-containing hindered amide compound used for light stabilizer and preparation method thereof BEIJING TIANGANG AUX Y CO LTD 2012-05-23 CN disclosed
US-20110104613-A1 Antireflective Composition for Photoresists MERCK PATENT GMBH (DE) 2011-05-05 US disclosed