SCHEMBL7203553

SCHEMBL7203553

C=CCOC(=O)Nc1nc2ccccc2[nH]1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB4A P04350 1/20 0.62
TUBB P07437 1/20 0.62
TUBA3C P0DPH7 1/20 0.62
TUBA1B P68363 1/20 0.62
TUBA4A P68366 1/20 0.62
TUBB4B P68371 1/20 0.62
TUBB3 Q13509 1/20 0.62
TUBB2A Q13885 1/20 0.62
TUBB8 Q3ZCM7 1/20 0.62
TUBA3E Q6PEY2 1/20 0.62
TUBA1A Q71U36 1/20 0.62
TUBA1C Q9BQE3 1/20 0.62
TUBB6 Q9BUF5 1/20 0.62
TUBB2B Q9BVA1 1/20 0.62
TUBB1 Q9H4B7 1/20 0.62
SMN1; SMN2 Q16637 5/20 0.56
LMNA P02545 3/20 0.56
CYP3A4 P08684 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
NPC1 O15118 8/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27450760 0.88 LMNA (0.57) SMN1; SMN2LMNACYP3A4NPC1RAB9A
SCHEMBL11810629 0.83 TUBB4A (0.70) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL11810614 0.83 TUBB4A (0.61) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
Lobendazole SCHEMBL29682294 0.82 LMNA (0.64) SMN1; SMN2LMNACYP3A4NPC1RAB9A
Lobendazole SCHEMBL205437 0.82 LMNA (0.64) SMN1; SMN2LMNACYP3A4NPC1RAB9A
SCHEMBL9398591 0.80 TUBB4A (0.51) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL28071882 0.80 CYP3A4 (0.65) SMN1; SMN2LMNACYP3A4NPC1RAB9A
SCHEMBL11868109 0.80 TUBB4A (0.65) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL3765821 0.79 LMNA (0.56) SMN1; SMN2LMNACYP3A4NPC1RAB9A
SCHEMBL11806582 0.79 LMNA (0.59) SMN1; SMN2LMNACYP3A4NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0933191-B1 Article based on vegetable fibers, suitable for the manufacture of vehicle parts VISTEON SYSTEMES INTERIEURS S (FR) 2002-07-10 EP claimed
EP-0016857-B1 MICROBICIDAL AGENT AND APPLICATION THEREOF BAYER AG (DE) 1982-06-09 EP claimed
US-3933846-A FUNGICIDES, OVICIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-01-20 US claimed
JP-8231313-A None JP disclosed
JP-58148804-A None JP disclosed
JP-61284588-A None JP disclosed
JP-2112473-A None JP disclosed
JP-3263472-A None JP disclosed
JP-62016404-A None JP disclosed
JP-58057367-A None JP disclosed
JP-1311168-A None JP disclosed
US-4026934-A INSECTICIDES, ACARICIDES, FUNGICIDES BAYER AKTIENGESELLSCHAFT (DT) 1977-05-31 US disclosed
US-3997553-A 2-Benzimidazolecarbamic acid esters by the cyanamide process E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-12-14 US disclosed
US-3978217-A OR 2 ACID ALKYLENE IMIDAZOLESFUNGICIDES CHINOIN GYOGYSZER-ES VEGYESZETI TERMEKEK GYARA RT (HU) 1976-08-31 US disclosed
US-3970668-A Dialkyl 1,1'-(optionally substituted hydrocarbylenebiscarbamoyl)bis(2-benzimidazolecarbamates) E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-07-20 US disclosed
US-3933846-A FUNGICIDES, OVICIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-01-20 US disclosed
US-3933846-A FUNGICIDES, OVICIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-01-20 US disclosed
US-3933846-A FUNGICIDES, OVICIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-01-20 US disclosed
US-3897448-A Process for the manufacture of alkyl benzimidazolylcarbamates RHONE PROGIL 1975-07-29 US disclosed
US-3897448-A Process for the manufacture of alkyl benzimidazolylcarbamates RHONE PROGIL 1975-07-29 US disclosed