Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 3/20 | 0.51 |
| ▸ | TUBB | P07437 | 3/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.51 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.51 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.51 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.51 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.51 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.51 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.51 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.51 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.51 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8954822 | 0.81 | CYP3A4 (0.48) | SMN1; SMN2LMNANPC1RAB9AHTT | |
| SCHEMBL7203553 | 0.80 | TUBB4A (0.62) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL11810614 | 0.79 | TUBB4A (0.61) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL11596452 | 0.75 | TUBB4A (0.54) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8954504 | 0.75 | KDR (0.57) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8954579 | 0.73 | NPC1 (0.46) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL11595216 | 0.73 | LMNA (0.62) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Hydrochloric Acid SCHEMBL9399211 | 0.72 | NPC1 (0.45) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3500740 | 0.72 | LMNA (0.55) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL11810629 | 0.72 | TUBB4A (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5278181-A | Parasiticides | BOARD OF REGENTS ACTING ON BEHALF OF THE UNIVERSITY OF MICHIGAN (US) | 1994-01-11 | — | — | US | disclosed |