Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.33 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.32 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4158422 | 0.84 | GAA (0.39) | HSPA5SMN1; SMN2ALDH1A1AKR1C3KDM4E | |
| SCHEMBL7200424 | 0.82 | SMN1; SMN2 (0.45) | HSPA5SMN1; SMN2ALDH1A1KDM4EMAPK1 | |
| SCHEMBL7200672 | 0.82 | CYP3A4 (0.37) | RARBSMN1; SMN2ALDH1A1CYP26A1CYP26B1 | |
| SCHEMBL7182928 | 0.81 | HSPA5 (0.53) | PTGS2HSPA5RARBSMN1; SMN2ALDH1A1 | |
| SCHEMBL7206085 | 0.80 | HSPA5 (0.36) | HSPA5RARBALDH1A1CYP26A1AKR1C3 | |
| SCHEMBL809386 | 0.76 | CYP1A2 (0.44) | PTGS2SMN1; SMN2ALDH1A1CYP26A1CYP26B1 | |
| SCHEMBL809463 | 0.76 | SMN1; SMN2 (0.42) | PTGS2HSPA5SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL4157787 | 0.75 | CYP1A2 (0.39) | PTGS2SMN1; SMN2ALDH1A1KDM4EMAPK1 | |
| SCHEMBL7203428 | 0.75 | RXRA (0.41) | RARBSMN1; SMN2ALDH1A1CYP26A1AKR1C3 | |
| SCHEMBL3219897 | 0.71 | HSPA5 (0.59) | HSPA5SMN1; SMN2ALDH1A1KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003045957-A1 | 3-BIPHENYL-SUBSTITUTED-3-SUBSTITUTED-4-KETOLACTAM AND KETOLACTONE AND THEIR UTILIZATION AS PESTICIDE | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2003-06-05 | — | — | WO | disclosed |
| US-6525120-B2 | Stabilization using bisphenol ester | SUMITOMO CHEMICAL CO., LTD. (JP) | 2003-02-25 | — | — | US | disclosed |
| US-20020002249-A1 | Polymer composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-01-03 | — | — | US | disclosed |