Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LSS | P48449 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 4/20 | 0.38 |
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4802756 | 0.88 | LSS (0.50) | MGLLMEN1KMT2ALSS | |
| SCHEMBL7203840 | 0.83 | LSS (0.47) | MGLLLSSNPC1CASP1RAB9A | |
| SCHEMBL7209252 | 0.79 | MAPK14 (0.41) | MEN1KMT2ALSS | |
| SCHEMBL27578412 | 0.78 | LSS (0.48) | MEN1KMT2ALSS | |
| SCHEMBL7211489 | 0.78 | NAAA (0.45) | CNR2CNR1 | |
| SCHEMBL28749500 | 0.77 | LSS (0.47) | MEN1KMT2ALSS | |
| SCHEMBL7209102 | 0.77 | TMEM97 (0.42) | MEN1KMT2ALSS | |
| SCHEMBL27596327 | 0.77 | LSS (0.53) | MEN1KMT2ALSS | |
| SCHEMBL27596423 | 0.74 | LSS (0.48) | MEN1KMT2ALSS | |
| SCHEMBL27596333 | 0.74 | LSS (0.54) | MEN1KMT2ALSSFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |