Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LSS | P48449 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7211489 | 0.91 | NAAA (0.45) | MAPK14KDM4EKDM5A | |
| SCHEMBL7209102 | 0.89 | TMEM97 (0.42) | MAPK14KDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL7209246 | 0.81 | LSS (0.45) | LSSMAOBTHRATHRB | |
| SCHEMBL7209249 | 0.81 | LSS (0.45) | LSSMAOBTHRATHRB | |
| SCHEMBL7203834 | 0.79 | MGLL (0.51) | MEN1KMT2ALSS | |
| SCHEMBL7210867 | 0.78 | LMNA (0.42) | ALDH1A1HPGDKMT2ALSSMAOB | |
| SCHEMBL7210863 | 0.78 | LMNA (0.42) | ALDH1A1HPGDKMT2ALSSMAOB | |
| SCHEMBL27596327 | 0.78 | LSS (0.53) | MAPK14MEN1KMT2ALSSHSPB1 | |
| SCHEMBL7204634 | 0.77 | LSS (0.43) | MAPK14LSSKDM5A | |
| SCHEMBL7204883 | 0.77 | LSS (0.43) | MAPK14LSSKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |