Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30926124 | 0.80 | ESR2 (0.42) | GAAL3MBTL1GABRG2GABRB3GABRA5 | |
| SCHEMBL3401714 | 0.80 | ESR2 (0.42) | GAAL3MBTL1GABRG2GABRB3GABRA5 | |
| Hydrochloric Acid SCHEMBL30510206 | 0.79 | ESR2 (0.41) | GAAL3MBTL1GABRG2GABRB3GABRA5 | |
| SCHEMBL7203832 | 0.78 | POLB (0.43) | MEN1KMT2ASMN1; SMN2PIN1ERBB2 | |
| SCHEMBL18300977 | 0.75 | MAP2K1 (0.41) | GAAL3MBTL1GABRG2GABRB3GABRA5 | |
| SCHEMBL2660490 | 0.73 | CTNNB1 (0.47) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3251181 | 0.72 | CYP1A2 (0.43) | MEN1KMT2ASMN1; SMN2PIN1ERBB2 | |
| SCHEMBL945479 | 0.71 | — | — | |
| SCHEMBL12100932 | 0.69 | HTR1A (0.44) | MEN1KMT2ASMN1; SMN2PIN1ERBB2 | |
| SCHEMBL11115046 | 0.69 | POLB (0.41) | MEN1KMT2ASMN1; SMN2PIN1ERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610726-B2 | Pyrazole derivative that mimics or agonizes hepatocyte growth factor/scatter factor; antiischemic agents | NORTH SHORE-LONG ISLAND JEWISH RESEARCH INSTITUTE | 2003-08-26 | — | — | US | disclosed |