Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 14/20 | 0.54 |
| ▸ | NPY1R | P25929 | 8/20 | 0.54 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.54 |
| ▸ | NPY2R | P49146 | 5/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.51 |
| ▸ | IL23R | Q5VWK5 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7209878 | 0.93 | NPY4R (0.56) | NPY4RNPY1RNPY5RNPY2ROPRD1 | |
| SCHEMBL7207013 | 0.93 | OPRD1 (0.49) | NPY4RNPY1RNPY5RNPY2ROPRD1 | |
| SCHEMBL14469627 | 0.91 | NPY4R (0.57) | NPY4RNPY1RNPY5RNPY2ROPRD1 | |
| SCHEMBL29461981 | 0.88 | NPY4R (0.66) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL7206228 | 0.88 | OPRD1 (0.65) | OPRD1OPRM1OPRK1 | |
| SCHEMBL31680261 | 0.87 | NPY4R (0.66) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL7207673 | 0.86 | CCKAR (0.50) | NPY4RNPY1RNPY5RNPY2ROPRD1 | |
| SCHEMBL7207681 | 0.86 | CCKAR (0.50) | NPY4RNPY1RNPY5RNPY2ROPRD1 | |
| SCHEMBL29541285 | 0.86 | NPY4R (0.69) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL30163459 | 0.85 | NPY4R (0.59) | NPY4RNPY1RNPY5RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644772-A4 | OPIOID PEPTIDES. | BIOMEASURE INC (US) | 1997-01-29 | — | — | EP | claimed |
| EP-0644772-A1 | OPIOID PEPTIDES | BIOMEASURE, INC. (US) | 1995-03-29 | — | — | EP | claimed |
| WO-1994011018-A1 | OPIOID PEPTIDES | BIOMEASURE, INC. (US) | 1994-05-26 | — | — | WO | claimed |
| EP-0644772-B1 | OPIOID PEPTIDES | SOD CONSEILS RECH APPLIC (FR) | 2003-04-02 | — | — | EP | disclosed |
| US-5663295-A | ANALGESIC, ANTIDIARRHEA | BIOMEASURE INC. (US) | 1997-09-02 | — | — | US | disclosed |
| EP-0644772-A4 | OPIOID PEPTIDES. | BIOMEASURE INC (US) | 1997-01-29 | — | — | EP | disclosed |
| EP-0644772-A1 | OPIOID PEPTIDES | BIOMEASURE, INC. (US) | 1995-03-29 | — | — | EP | disclosed |
| WO-1994011018-A1 | OPIOID PEPTIDES | BIOMEASURE, INC. (US) | 1994-05-26 | — | — | WO | disclosed |