SCHEMBL29541285

SCHEMBL29541285

CSCC[C@H](N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(N)=O

nearest known ligand 0.69

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 15/20 0.69
▸ NPY1R P25929 9/20 0.69
▸ NPY5R Q15761 8/20 0.69
▸ NPY2R P49146 5/20 0.69
▸ KISS1R Q969F8 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30401277 0.95 NPY4R (0.64) NPY4RNPY1RNPY5RNPY2R
SCHEMBL3386701 0.93 NPY4R (0.62) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL29462004 0.91 NPY4R (0.62) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29461981 0.90 NPY4R (0.66) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29641080 0.90 NPY4R (0.80) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL29352845 0.89 FNTA (0.58) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29619346 0.89 FNTA (0.60) NPY4RNPY1RNPY5RNPY2R
SCHEMBL38660333 0.88 NPY4R (0.58) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30163459 0.88 NPY4R (0.59) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL28091113 0.88 NPY4R (0.59) NPY4RNPY1RNPY5RNPY2RKISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4711005-A2 METHODS FOR REDUCING RISKS ASSOCIATED WITH HEART FAILURE AND FACTORS ASSOCIATED THEREWITH Stealth BioTherapeutics Inc. (US) 2026-03-18 — — EP disclosed
US-20260061023-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION OR TREATMENT OF BARTH SYNDROME STEALTH BIOTHERAPEUTICS INC. (US) 2026-03-05 — — US disclosed
US-20260062752-A1 METHODS AND COMPOSITIONS FOR DETECTING AND DIAGNOSING DISEASES AND CONDITIONS STEALTH BIOTHERAPEUTICS INC. (US) 2026-03-05 — — US disclosed
US-20250276116-A1 METHODS OF MITIGATING MYOCARDIAL DAMAGE DUE TO EXTRACORPOREAL MEMBRANE OXYGENATION TUFTS MEDICAL CENTER, INC. 2025-09-04 — — US disclosed
US-20250255929-A1 METHODS FOR REDUCING RISKS ASSOCIATED WITH HEART FAILURE AND FACTORS ASSOCIATED THEREWITH STEALTH BIOTHERAPEUTICS INC. (US) 2025-08-14 — — US disclosed
US-12337023-B2 Methods and compositions for the prevention and treatment of disease STEALTH BIOTHERAPEUTICS INC. (US) 2025-06-24 — — US disclosed
US-20250161401-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY STEALTH BIOTHERAPEUTICS INC. (US) 2025-05-22 — — US disclosed
US-12297502-B2 Methods and compositions for detecting and diagnosing diseases and conditions STEALTH BIOTHERAPEUTICS INC. (US) 2025-05-13 — — US disclosed
US-12268724-B2 Methods and compositions for the prevention or treatment of Barth Syndrome STEALTH BIOTHERAPEUTICS INC. (US) 2025-04-08 — — US disclosed
US-20250109167-A1 METHODS FOR THE TREATMENT OF MITOCHONDRIAL DISEASE STEALTH BIOTHERAPEUTICS INC. (US) 2025-04-03 — — US disclosed
US-20230109564-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY STEALTH BIOTHERAPEUTICS INC. (US) 2023-04-06 — — US disclosed
US-20230043587-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DISEASE STEALTH BIOTHERAPEUTICS INC. (US) 2023-02-09 — — US disclosed
US-20230033758-A1 METHODS AND COMPOSITIONS FOR DETECTING AND DIAGNOSING DISEASES AND CONDITIONS STEALTH BIOTHERAPEUTICS INC. (US) 2023-02-02 — — US disclosed
EP-4085920-A1 METHODS FOR THE TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY Stealth BioTherapeutics Inc. (US) 2022-11-09 — — EP disclosed
US-11420998-B2 Aromatic-cationic peptides and methods for using same STEALTH BIOTHERAPEUTICS INC. (US) 2022-08-23 — — US disclosed
US-11376304-B2 Methods and compositions for the prevention and treatment of disease STEALTH BIOTHERAPEUTICS INC. (US) 2022-07-05 — — US disclosed
US-11366104-B2 Methods of identifying and monitoring mitochondrial dysfunction using monocyte screening STEALTH BIOTHERAPEUTICS INC. (US) 2022-06-21 — — US disclosed
EP-4005582-A1 TREATMENT OF LEFT VENTRICULAR REMODELING Stealth BioTherapeutics Inc. (US) 2022-06-01 — — EP disclosed
EP-4000690-A1 COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF MITOCHONDRIAL MYOPATHIES Stealth BioTherapeutics Inc. (US) 2022-05-25 — — EP disclosed
US-11312993-B2 Methods and compositions for detecting and diagnosing diseases and conditions STEALTH BIOTHERAPEUTICS INC. (US) 2022-04-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230043587-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DISEASE COL2A1, ALPI, COL14A1 NPY4R 223/4885NPY1R 735/4885NPY5R 484/4885
US-20250109167-A1 METHODS FOR THE TREATMENT OF MITOCHONDRIAL DISEASE NLN, OAT, HAGH NPY4R 693/4885NPY1R 649/4885NPY5R 976/4885
US-20260061023-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION OR TREATMENT OF BARTH SYNDROME ARG2, ARGLU1, BCAT1 NPY4R 2600/4885NPY1R 872/4885NPY5R 1341/4885
US-20250255929-A1 METHODS FOR REDUCING RISKS ASSOCIATED WITH HEART FAILURE AND FACTORS ASSOCIATED THEREWITH TNNI3, TNNT2, FABP3 NPY4R 2454/4885NPY1R 1553/4885NPY5R 2704/4885
US-12337023-B2 Methods and compositions for the prevention and treatment of disease COL2A1, ALPI, COL14A1 NPY4R 223/4885NPY1R 735/4885NPY5R 484/4885
US-20250161401-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY MTPN, UTRN, SMN1; SMN2 NPY4R 2905/4885NPY1R 2251/4885NPY5R 2474/4885
US-20230109564-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY MTPN, UTRN, SMN1; SMN2 NPY4R 2905/4885NPY1R 2251/4885NPY5R 2474/4885
US-11420998-B2 Aromatic-cationic peptides and methods for using same ARG2, ARGLU1, ARG1 NPY4R 824/4885NPY1R 523/4885NPY5R 1077/4885
US-20260062752-A1 METHODS AND COMPOSITIONS FOR DETECTING AND DIAGNOSING DISEASES AND CONDITIONS ARG2, MTPN, TNNT2 NPY4R 3734/4885NPY1R 3368/4885NPY5R 3526/4885
US-11376304-B2 Methods and compositions for the prevention and treatment of disease COL2A1, ALPI, COL14A1 NPY4R 223/4885NPY1R 735/4885NPY5R 484/4885
US-20250276116-A1 METHODS OF MITIGATING MYOCARDIAL DAMAGE DUE TO EXTRACORPOREAL MEMBRANE OXYGENATION TNNI3, TNNT2, MB NPY4R 4783/4885NPY1R 4818/4885NPY5R 4367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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