SCHEMBL14469627

SCHEMBL14469627

CSCCC(NC(=O)C(N)Cc1ccc(O)cc1)C(=O)NCC(=O)NC(CO)C(=O)NC(CCCNC(=N)N)C(N)=O

nearest known ligand 0.57

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 15/20 0.57
▸ NPY1R P25929 9/20 0.57
▸ NPY5R Q15761 8/20 0.57
▸ NPY2R P49146 5/20 0.57
▸ OPRM1 P35372 1/20 0.53
▸ OPRD1 P41143 1/20 0.53
▸ OPRK1 P41145 1/20 0.53
▸ IL23R Q5VWK5 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29461981 0.91 NPY4R (0.66) NPY4RNPY1RNPY5RNPY2R
SCHEMBL7203848 0.91 NPY4R (0.54) NPY4RNPY1RNPY5RNPY2ROPRM1
SCHEMBL31680261 0.90 NPY4R (0.66) NPY4RNPY1RNPY5RNPY2R
SCHEMBL14450436 0.88 NPY4R (0.52) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30668292 0.87 OPRM1 (0.55) NPY4RNPY1RNPY5RNPY2ROPRM1
SCHEMBL7207013 0.87 OPRD1 (0.49) NPY4RNPY1RNPY5RNPY2ROPRM1
SCHEMBL31256983 0.84 NPY4R (0.55) NPY4RNPY1RNPY5RNPY2ROPRM1
SCHEMBL32685406 0.83 NPY4R (0.60) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30787055 0.83 NPY4R (0.60) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29476428 0.83 NPY4R (0.60) NPY4RNPY1RNPY5RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070172422-A1 Exponential pattern recognition based cellular targeting compositions, methods and anticancer applications GLAZIER ARNOLD 2007-07-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070172422-A1 Exponential pattern recognition based cellular targeting compositions, methods and anticancer applications EPHA2, EEA1, HAVCR2 NPY4R 4332/4885NPY1R 4277/4885NPY5R 4431/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback