Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 5/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27518665 | 0.90 | ADORA1 (0.43) | ADORA1ADORA3ADORA2AADORA2BTP53 | |
| SCHEMBL28165438 | 0.84 | ADORA1 (0.45) | ADORA1ADORA3ADORA2AADORA2BTP53 | |
| SCHEMBL4581732 | 0.79 | ADORA3 (0.49) | ADORA1ADORA3ADORA2AADORA2BSLC29A1 | |
| SCHEMBL28023787 | 0.79 | ADORA3 (0.48) | ADORA1ADORA3ADORA2AADORA2BTP53 | |
| SCHEMBL28423217 | 0.79 | ADORA1 (0.40) | ADORA1ADORA3ADORA2AADORA2BSLC29A1 | |
| SCHEMBL29834227 | 0.77 | ADORA1 (0.39) | ADORA1 | |
| SCHEMBL6908906 | 0.77 | ADORA1 (0.41) | ADORA1ADORA3ADORA2AADORA2BTP53 | |
| SCHEMBL31677375 | 0.77 | ADORA1 (0.41) | ADORA1ADORA3ADORA2AADORA2BTP53 | |
| SCHEMBL13268913 | 0.77 | ADORA3 (0.60) | ADORA1ADORA3ADORA2AADORA2BTP53 | |
| SCHEMBL6402247 | 0.77 | ADORA1 (0.39) | ADORA1ADORA3ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030232977-A1 | Antisense modulation of splicing factor R/S-rich 10 expression | ISIS PHARMACEUTICALS INC. | 2003-12-18 | — | — | US | disclosed |