Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.54 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.54 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.54 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | RRM1 | P23921 | 1/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27428520 | 1.00 | GNAI3 (0.54) | GNAI3GNAO1GNAI1DNM1MEN1 | |
| SCHEMBL28676201 | 1.00 | GNAI3 (0.54) | GNAI3GNAO1GNAI1DNM1MEN1 | |
| SCHEMBL7205302 | 0.98 | GNAI3 (0.51) | GNAI3GNAO1GNAI1DNM1MEN1 | |
| SCHEMBL6021971 | 0.94 | GNAI3 (0.47) | GNAI3GNAO1GNAI1DNM1MEN1 | |
| SCHEMBL9691923 | 0.92 | OPRM1 (0.46) | GNAI3GNAO1GNAI1ALDH1A1TSHR | |
| SCHEMBL28542120 | 0.92 | OPRM1 (0.46) | GNAI3GNAO1GNAI1ALDH1A1TSHR | |
| SCHEMBL27146358 | 0.92 | OPRM1 (0.46) | GNAI3GNAO1GNAI1ALDH1A1TSHR | |
| SCHEMBL28985254 | 0.92 | OPRM1 (0.46) | GNAI3GNAO1GNAI1ALDH1A1TSHR | |
| SCHEMBL9163909 | 0.92 | OPRM1 (0.46) | GNAI3GNAO1GNAI1ALDH1A1TSHR | |
| SCHEMBL28116311 | 0.92 | OPRM1 (0.46) | GNAI3GNAO1GNAI1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912584-B1 | NEW BIS-PLATINUM COMPLEXES WITH POLYAMINE LIGANDS AS ANTITUMOR AGENTS | HOFFMANN LA ROCHE (CH) | 2002-12-18 | — | — | EP | disclosed |
| US-6022892-A | Bis-platinum complexes with polyamine ligands as antitumor agents | HOFFMAN-LA ROCHE INC. (US) | 2000-02-08 | — | — | US | disclosed |
| EP-0912584-A2 | NEW BIS-PLATINUM COMPLEXES WITH POLYAMINE LIGANDS AS ANTITUMOR AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998003519-A9 | NEW BIS-PLATINUM COMPLEXES WITH POLYAMINE LIGANDS AS ANTITUMOR AGENTS | — | 1998-07-16 | — | — | WO | disclosed |
| WO-1998003519-A2 | NEW BIS-PLATINUM COMPLEXES WITH POLYAMINE LIGANDS AS ANTITUMOR AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 1998-01-29 | — | — | WO | disclosed |