Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | KDM4A | O75164 | 1/20 | 0.56 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28891861 | 0.93 | TSHR (0.58) | ALDH1A1TSHRLMNATP53CYP3A4 | |
| SCHEMBL719806 | 0.85 | ALDH1A1 (0.55) | ALDH1A1TSHRLMNATP53CYP3A4 | |
| SCHEMBL27684582 | 0.81 | LMNA (0.62) | ALDH1A1TSHRLMNATP53CYP3A4 | |
| SCHEMBL29184950 | 0.81 | LMNA (0.62) | ALDH1A1TSHRLMNATP53CYP3A4 | |
| SCHEMBL5935797 | 0.81 | LMNA (0.62) | ALDH1A1TSHRLMNATP53CYP3A4 | |
| SCHEMBL11148883 | 0.81 | LMNA (0.62) | ALDH1A1TSHRLMNATP53CYP3A4 | |
| SCHEMBL1269440 | 0.79 | APP (0.63) | ALDH1A1TSHRLMNATP53CYP3A4 | |
| Calcium SCHEMBL2689056 | 0.78 | APP (0.61) | ALDH1A1TSHRLMNATP53CYP3A4 | |
| SCHEMBL11005679 | 0.75 | TSHR (0.63) | ALDH1A1TSHRLMNATP53CYP3A4 | |
| SCHEMBL11001210 | 0.75 | TSHR (0.63) | ALDH1A1TSHRLMNATP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120115724-A1 | METHOD OF CONTROLLING UNDESIRED VEGETATION | SYNGENTA CROP PROTECTION LLC (US) | 2012-05-10 | — | — | US | disclosed |
| US-20120053053-A1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION, LLC (US) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053053-A1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS HERBICIDES | DPYD, DHODH, TYMP | ALDH1A1 1043/4885TSHR 1099/4885LMNA 4613/4885 |
| US-20120115724-A1 | METHOD OF CONTROLLING UNDESIRED VEGETATION | TYMS, DHFR, UNG | ALDH1A1 3537/4885TSHR 2909/4885LMNA 2223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.