SCHEMBL7204090

SCHEMBL7204090

CCCC[C@H](N)C(=O)N[C@H]([C]=O)Cc1cc(Cl)cc(Cl)c1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CTSC P53634 5/20 0.46
DPP7 Q9UHL4 9/20 0.43
DPP9 Q86TI2 8/20 0.43
DPP8 Q6V1X1 7/20 0.43
DPP4 P27487 5/20 0.43
SLC15A1 P46059 1/20 0.40
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CTSH P09668 1/20 0.37
CYP2D6 P10635 1/20 0.37
CTSK P43235 1/20 0.37
CHEK1 O14757 1/20 0.37
ERAP2 Q6P179 2/20 0.37
LNPEP Q9UIQ6 2/20 0.37
OPRM1 P35372 2/20 0.37
OPRD1 P41143 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7592014 0.85 CTSC (0.46) CTSCDPP7DPP9DPP8DPP4
SCHEMBL7586126 0.82 CTSC (0.44) CTSCDPP7DPP9DPP8DPP4
SCHEMBL2182387 0.78 DPP7 (0.57) DPP7DPP9DPP8DPP4SLC15A1
SCHEMBL9828439 0.78 CTSC (0.57) CTSCCYP1A2CYP3A4CTSHCYP2D6
SCHEMBL7613327 0.74 DPP7 (0.58) CTSCDPP7DPP9DPP8DPP4
SCHEMBL2182283 0.72 CTSC (0.60) CTSCCYP1A2CYP3A4CTSHCYP2D6
SCHEMBL10520841 0.72 DPP7 (0.62) DPP7DPP9DPP8DPP4SLC15A1
SCHEMBL7588339 0.71 MMP2 (0.43) CTSCDPP7DPP9DPP8DPP4
SCHEMBL8721584 0.71 DPP7 (0.58) CTSCDPP7DPP9DPP8DPP4
SCHEMBL7591254 0.71 HDAC8 (0.41) CTSCDPP7DPP9DPP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030114362-A1 Penta-or tetrapeptide binding to somatostatin receptors and the use of the same NOVASPIN BIOTECH GMBH (DE) 2003-06-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030114362-A1 Penta-or tetrapeptide binding to somatostatin receptors and the use of the same SSTR5, SSTR3, SCTR CTSC 83/4885DPP7 191/4885DPP9 285/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.