SCHEMBL7586126

SCHEMBL7586126

CCCC[C@H](N)C(=O)N[C@H]([C]=O)Cc1cc(Cl)ccc1Cl

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CTSC P53634 1/20 0.44
HDAC8 Q9BY41 5/20 0.43
DPP7 Q9UHL4 5/20 0.40
DPP8 Q6V1X1 4/20 0.40
DPP9 Q86TI2 4/20 0.40
DPP4 P27487 3/20 0.40
CHEK1 O14757 1/20 0.38
SLC15A1 P46059 1/20 0.37
ERAP2 Q6P179 3/20 0.37
LNPEP Q9UIQ6 2/20 0.37
KCNH2 Q12809 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7591254 0.89 HDAC8 (0.41) CTSCHDAC8DPP7DPP8DPP9
SCHEMBL7592014 0.84 CTSC (0.46) CTSCDPP7DPP8DPP9DPP4
SCHEMBL7204090 0.82 CTSC (0.46) CTSCDPP7DPP8DPP9DPP4
SCHEMBL2182387 0.76 DPP7 (0.57) DPP7DPP8DPP9DPP4CHEK1
SCHEMBL7591965 0.75 MMP2 (0.47) CTSCHDAC8DPP7DPP8DPP9
SCHEMBL9828439 0.73 CTSC (0.57) CTSC
SCHEMBL7613327 0.72 DPP7 (0.58) CTSCDPP7DPP8DPP9DPP4
SCHEMBL7032724 0.71 HDAC8 (0.50) HDAC8
SCHEMBL7032727 0.71 HDAC8 (0.50) HDAC8
SCHEMBL2182283 0.70 CTSC (0.60) CTSC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002100885-A2 A PENTA- OR TETRAPEPTIDE BINDING TO SOMATOSTATIN RECEPTORS AND THE USE OF THE SAME NOVASPIN BIOTECH GMBH (DE) 2002-12-19 WO disclosed