SCHEMBL7204095

SCHEMBL7204095

CC(=O)c1[nH]c2cc(Cl)ccc2c1CC(=O)O

nearest known ligand 0.79

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 3/20 0.60
GPR17 Q13304 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9187231 0.88 GPR17 (0.74) PTGS2GPR17
SCHEMBL6169004 0.83 PTGS2 (0.60) PTGS2GPR17
SCHEMBL9449409 0.83 ALOX15 (0.66) PTGS2
SCHEMBL6287665 0.82 KDM4E (0.63) PTGS2GPR17
SCHEMBL6169769 0.82 PTGS2 (0.59) PTGS2GPR17
SCHEMBL6170593 0.82 PTGS2 (0.59) PTGS2GPR17
SCHEMBL6171162 0.81 PTGS2 (0.54) PTGS2GPR17
SCHEMBL6171874 0.81 PTGS2 (0.61) PTGS2GPR17
SCHEMBL6170150 0.80 PTGS2 (0.57) PTGS2GPR17
SCHEMBL6169720 0.80 PTGS2 (0.57) PTGS2GPR17

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6608070-B1 Useful for treatment of medical condition in which prostaglandins are implicated as pathogens NAKAO KAZUNARI (JP) 2003-08-19 US disclosed