Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9189433 | 0.90 | ALDH1A1 (0.65) | ALOX15 | |
| SCHEMBL9449437 | 0.90 | ALOX15 (0.66) | ALOX15 | |
| SCHEMBL9449317 | 0.89 | ALOX15 (0.65) | ALOX15 | |
| SCHEMBL4573082 | 0.86 | ALOX15 (0.67) | ALOX15 | |
| SCHEMBL15622440 | 0.84 | ALOX15 (0.65) | ALOX15 | |
| SCHEMBL15622620 | 0.83 | ALOX15 (0.64) | ALOX15 | |
| SCHEMBL3029308 | 0.83 | ALOX15 (0.74) | ALOX15 | |
| SCHEMBL4042096 | 0.83 | ALOX15 (0.74) | ALOX15 | |
| SCHEMBL7204095 | 0.83 | PTGS2 (0.60) | PTGS2 | |
| SCHEMBL9187231 | 0.83 | GPR17 (0.74) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5229413-A | Nervous system disorders | G. D. SEARLE & CO. (US) | 1993-07-20 | — | — | US | disclosed |
| US-5137910-A | Compositions containing indole-2-carboxylate compounds for treatment of CNS disorders | C.D. SEARLE & CO. (US) | 1992-08-11 | — | — | US | disclosed |