Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2525981 | 0.85 | ALDH1A1 (0.60) | ALDH1A1HPGDSMN1; SMN2HTTKMT2A | |
| SCHEMBL19304098 | 0.82 | ALDH1A1 (0.69) | ALDH1A1HPGDSMN1; SMN2HTTKMT2A | |
| SCHEMBL2814838 | 0.81 | PRMT6 (0.46) | ALDH1A1HPGDKMT2A | |
| SCHEMBL30633831 | 0.78 | ALDH1A1 (0.79) | ALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL4844448 | 0.78 | HTT (0.58) | ALDH1A1HPGDSMN1; SMN2HTTKMT2A | |
| SCHEMBL28882986 | 0.77 | SMN1; SMN2 (0.57) | ALDH1A1HPGDSMN1; SMN2HTTKMT2A | |
| SCHEMBL7456756 | 0.74 | SMN1; SMN2 (0.64) | ALDH1A1HPGDSMN1; SMN2HTTKMT2A | |
| SCHEMBL8293397 | 0.74 | HTT (0.71) | ALDH1A1HPGDSMN1; SMN2HTTKMT2A | |
| SCHEMBL15415933 | 0.74 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2HTTKMT2ALMNA | |
| SCHEMBL27477777 | 0.74 | PRMT6 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363668-A2 | COMBINATIONS OF BILE ACID SEQUESTRANT(S) AND STEROL ABSORPTION INHIBITOR(S) AND TREATMENTS FOR VASCULAR INDICATIONS | Schering Corporation (US) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002058733-A2 | COMBINATIONS OF BILE ACID SEQUESTRANT(S) AND STEROL ABSORPTION INHIBITOR(S) AND TREATMENTS FOR VASCULAR INDICATIONS | SCHERING CORPORATION (US) | 2002-08-01 | — | — | WO | disclosed |