Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7598991 | 0.83 | ALDH1A1 (0.68) | ALDH1A1KDM4EMEN1PABPC1KMT2A | |
| SCHEMBL10044901 | 0.82 | ALDH1A1 (0.67) | ALDH1A1KDM4EMEN1PABPC1KMT2A | |
| SCHEMBL1685962 | 0.81 | ALDH1A1 (0.65) | ALDH1A1KDM4EMEN1PABPC1KMT2A | |
| SCHEMBL7597398 | 0.81 | ALDH1A1 (0.65) | ALDH1A1KDM4EMEN1PABPC1KMT2A | |
| SCHEMBL6996658 | 0.80 | ALDH1A1 (0.64) | ALDH1A1KDM4EMEN1PABPC1KMT2A | |
| SCHEMBL7200053 | 0.79 | HDAC4 (0.54) | ALDH1A1KDM4EMEN1PABPC1KMT2A | |
| SCHEMBL7617278 | 0.79 | ALDH1A1 (0.62) | ALDH1A1KDM4EMEN1PABPC1KMT2A | |
| SCHEMBL7614893 | 0.79 | ALDH1A1 (0.62) | ALDH1A1KDM4EMEN1PABPC1KMT2A | |
| SCHEMBL5165226 | 0.79 | ALDH1A1 (0.62) | ALDH1A1KDM4EMEN1PABPC1KMT2A | |
| SCHEMBL7249971 | 0.79 | MAPT (0.49) | ALDH1A1KDM4EMEN1PABPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6605616-B1 | Autoimmune diseases; inflammation | ACTIVE BIOTECH AB (SE) | 2003-08-12 | — | — | US | disclosed |