SCHEMBL7204828

SCHEMBL7204828

Cc1ccc(C(=O)O)c(C)c1Cc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
IDH1 O75874 1/20 0.47
HNF4A P41235 1/20 0.44
ALDH1A1 P00352 1/20 0.42
PTPN1 P18031 4/20 0.41
NOTUM Q6P988 2/20 0.41
PTPN2 P17706 1/20 0.41
PTPN6 P29350 1/20 0.41
PTGER1 P34995 1/20 0.41
LDHA P00338 1/20 0.41
LDHB P07195 1/20 0.41
HTT P42858 1/20 0.41
LMNA P02545 1/20 0.41
PTGER4 P35408 1/20 0.40
TSHR P16473 1/20 0.40
KAT8 Q9H7Z6 1/20 0.40
FABP4 P15090 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17941538 0.85 ALDH1A1 (0.49) IDH1HNF4AALDH1A1PTPN1PTPN2
SCHEMBL7203043 0.85 IDH1 (0.46) IDH1HNF4AALDH1A1PTPN1NOTUM
SCHEMBL28910537 0.83 ALDH1A1 (0.35) IDH1HNF4AALDH1A1LMNAPTGER4
SCHEMBL7197330 0.82 ALDH1A1 (0.42) IDH1HNF4AALDH1A1PTPN1NOTUM
SCHEMBL27383635 0.81 ALDH1A1 (0.45) IDH1HNF4AALDH1A1PTPN1NOTUM
SCHEMBL3271724 0.81 ALDH1A1 (0.52) IDH1HNF4AALDH1A1PTPN1PTPN2
SCHEMBL28531372 0.81 CYP4F2 (0.45) ALDH1A1LMNA
SCHEMBL7036187 0.80 ALDH1A1 (0.42) IDH1HNF4AALDH1A1PTPN1NOTUM
SCHEMBL26502 0.79 HNF4A (0.53) HNF4AALDH1A1PTPN1PTPN2PTPN6
SCHEMBL31345536 0.79 IDH1 (0.49) IDH1ALDH1A1HTTLMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003078377-A1 OXIDATION OF O-XYLOL TO FORM O-TOLUIC AND OTHER OXIDATION PRODUCTS BY THE CONTROLLED SUPPLY OF AN OXYGEN-CONTAINING GAS BASF AKTIENGESELLSCHAFT (DE) 2003-09-25 WO disclosed
WO-2003078369-A1 OXIDATION OF O-XYLOL TO FORM O-TOLUIC ACID AND OTHER OXIDATION PRODUCTS BY THE STAGGERED SUPPLY OF AN OXYGEN-CONTAINING GAS BASF AKTIENGESELLSCHAFT (DE) 2003-09-25 WO disclosed